Evidence map›Paper›PMID 34758032›Full record

Observational studyPloS one2021

Laminar flow ventilation system to prevent airborne infection during exercise in the COVID-19 crisis: A single-center observational study.

Yoshinori Katsumata, Motoaki Sano, Hiroki Okawara, Tomonori Sawada, Daisuke Nakashima, Genki Ichihara, Keiichi Fukuda, Kazuki Sato, Eiji Kobayashi

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

  1. Trial
  2. Article
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  6. Review
  7. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Yoshinori KatsumataInstitute for Integrated Sports Medicine, Keio University School of Medicine, Tokyo, Japan.ORCID 0000-0001-5576-5789
Motoaki SanoDepartment of Cardiology, Keio University School of Medicine, Tokyo, Japan.
Hiroki OkawaraDepartment of Orthopaedic Surgery, Keio University School of Medicine, Tokyo, Japan.
Tomonori SawadaDepartment of Orthopaedic Surgery, Keio University School of Medicine, Tokyo, Japan.
Daisuke NakashimaDepartment of Orthopaedic Surgery, Keio University School of Medicine, Tokyo, Japan.ORCID 0000-0003-1105-2669
Genki IchiharaDepartment of Cardiology, Keio University School of Medicine, Tokyo, Japan.
Keiichi FukudaDepartment of Cardiology, Keio University School of Medicine, Tokyo, Japan.
Kazuki SatoInstitute for Integrated Sports Medicine, Keio University School of Medicine, Tokyo, Japan.
Eiji KobayashiDepartment of Organ Fabrication, Keio University School of Medicine, Tokyo, Japan.
Keio University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Particulate generation occurs during exercise-induced exhalation, and research on this topic is scarce. Moreover, infection-control measures are inadequately implemented to avoid particulate generation. A laminar airflow ventilation system (LFVS) was developed to remove respiratory droplets released during treadmill exercise. This study aimed to investigate the relationship between the number of aerosols during training on a treadmill and exercise intensity and to elucidate the effect of the LFVS on aerosol removal during anaerobic exercise. In this single-center observational study, the exercise tests were performed on a treadmill at Running Science Lab in Japan on 20 healthy subjects (age: 29±12 years, men: 80%). The subjects had a broad spectrum of aerobic capacities and fitness levels, including athletes, and had no comorbidities. All of them received no medication. The exercise intensity was increased by 1-km/h increments until the heart rate reached 85% of the expected maximum rate and then maintained for 10 min. The first 10 subjects were analyzed to examine whether exercise increased the concentration of airborne particulates in the exhaled air. For the remaining 10 subjects, the LFVS was activated during constant-load exercise to compare the number of respiratory droplets before and after LFVS use. During exercise, a steady amount of particulates before the lactate threshold (LT) was followed by a significant and gradual increase in respiratory droplets after the LT, particularly during anaerobic exercise. Furthermore, respiratory droplets ≥0.3 μm significantly decreased after using LFVS (2120800±759700 vs. 560 ± 170, p<0.001). The amount of respiratory droplets significantly increased after LT. The LFVS enabled a significant decrease in respiratory droplets during anaerobic exercise in healthy subjects. This study's findings will aid in exercising safely during this pandemic.

Indexed as

AdultAerosolsAir ConditioningAir FiltersAnaerobic ThresholdCOVID-19ExerciseExercise TestExhalationFemaleHeart RateHumansJapanLactic AcidMaleOxygen ConsumptionAerosolsLactic AcidParticulate Matter

Identifiers

PMID34758032
PMCPMC8580245
OpenAlexW3211939942

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.