ArticleJournal of acquired immune deficiency syndromes (1999)2021
Impact of the COVID-19 Pandemic on Use of HIV Care, Antiretroviral Therapy Adherence, and Viral Suppression: An Observational Cohort Study From Uganda.
Article in Journal of acquired immune deficiency syndromes (1999), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 4 of them syntheses that pooled it.
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Who cites it
42 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Repercussions of the COVID-19 pandemic on the HIV care continuum and related factors in economically disadvantaged nations: an integrated analysis using mixed-methods systematic review.European journal of medical research · 2024Pooled it
- Impact of COVID-19 Pandemic on Adherence to Chronic Therapies: A Systematic Review.International journal of environmental research and public health · 2023Pooled it
- The impacts of COVID-19 pandemic on service delivery and treatment outcomes in people living with HIV: a systematic review.AIDS research and therapy · 2023Pooled it
- Syndemic effect of COVID-19 outbreak on HIV care delivery around the globe: A systematic review using narrative synthesis.Health promotion perspectives · 2023Pooled it
- How Central Ugandan HIV Clinics Adapted During COVID-19 Lockdown Restrictions to Promote Continuous Access to Care: A Qualitative Analysis.AIDS and behavior · 2023Trial
- A multilevel health system intervention for virological suppression in adolescents and young adults living with HIV in rural Kenya and Uganda (SEARCH-Youth): a cluster randomised trial.The lancet. HIV · 2023Trial
- Food Insecurity During the COVID-19 Pandemic: A Longitudinal Mixed-Methods Study from a Cohort of HIV Clients in Uganda.AIDS and behavior · 2023Trial
- Mental Health Stressors of the COVID-19 Pandemic Negatively Affect Self-Management of Comorbid Cardiovascular Disease Among Persons Living With HIV in the United States: A Qualitative Study.The Journal of the Association of Nurses in AIDS Care : JANACTrial
- Observational
- Longitudinal challenges faced by perinatally-infected young people with HIV in Kenya during the COVID-19 pandemic.AIDS (London, England) · 2026Article
- Second-line antiretroviral therapy success rates and predictors among people living with HIV in Rwanda, 2019-2023.BMC infectious diseases · 2026Article
- Sleep quality and disturbance during the COVID-19 pandemic among people with HIV globally: associations with social determinants of health.AIDS (London, England) · 2026Observational
- The Ripple Effect of COVID-19: How Lockdown Regulations Shaped Antiretroviral Therapy Initiation Among People Living With HIV in Johannesburg.Nursing & health sciences · 2025Article
- Factors associated with mortality among people with advanced HIV disease in rural uganda: a retrospective study.BMC infectious diseases · 2025Article
- Rapid Antiretroviral Therapy Initiation Reduces Mortality Among People Living With HIV in Indonesia: A Retrospective Observational Study.Journal of preventive medicine and public health = Yebang Uihakhoe chi · 2025Observational
- Association between changes in script renewal periods and HIV viral non-suppression: a cohort study of a South African private-sector HIV program.Journal of acquired immune deficiency syndromes (1999) · 2025Article
- Impact of COVID-19 Public Health Measures on Antiretroviral Therapy Use Among Ugandans Living with HIV in Sero-Different Couples.AIDS and behavior · 2025Observational
- Article
- Disrupted HIV care during COVID-19 pandemic associated with increased disabilities among people living with HIV in Belize.Scientific reports · 2025Article
- Assessing the impact of the COVID-19 pandemic on uptake of HIV treatment in Bandung and Yogyakarta, Indonesia: A retrospective cohort study.PLOS global public health · 2025Article
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Authors and funding
6 authors.
Funding
Abstract
introductionRecent studies project thousands of additional AIDS-related deaths because of COVID-19-related disruptions in HIV care. However, the extent to which disruptions in care have materialized since the start of the pandemic is not well understood.
methodsWe use electronic health records to investigate how the pandemic has affected clinic visits, patients' antiretroviral therapy (ART) supply, and viral suppression for a cohort of 14,632 HIV clients from a large HIV clinic in Kampala, Uganda. We complement this with an analysis of electronically measured longitudinal ART adherence data from a subcohort of 324 clients.
resultsClinic visits decreased by more than 50% after a national lockdown started. The risk of patients running out of ART on a given day increased from 5% before the lockdown to 25% 3 months later (Relative Risk Ratio of 5.11, 95% confidence interval: 4.99 to 5.24) and remained higher than prelockdown 6 months later at 13% (Relative Risk Ratio of 2.60; 95% confidence interval: 2.52 to 2.70). There was no statistically significant change in electronically measured adherence or viral suppression.
conclusionWe document substantial gaps in HIV care after the start of the COVID-19 pandemic in Uganda. This suggests that measures to improve access should be explored as the pandemic persists. However, ART adherence was unaffected for the subcohort for whom we measured electronic adherence. This suggests that some clients may have stockpiles of ART tablets from previous prescriptions that allowed them to keep taking their medication even when they could not visit the clinic for ART refills.
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