Evidence map›Paper›PMID 34757836›Full record

ArticleJournal of virology2022

Proteolytic Processing of Plant Proteins by Potyvirus NIa Proteases.

Huogen Xiao, Etienne Lord, Hélène Sanfaçon

Open access · hybridAbstract read
In one paragraph

Article in Journal of virology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
4.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Cowpea lipid transfer protein 1 regulates plant defense by inhibiting the cysteine protease of cowpea mosaic virus.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  9. Review
  10. Article
  11. The Mechanism of Resistance of EUROPEAN Plum toPlants (Basel, Switzerland) · 2023
    Article
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Huogen XiaoSummerland Research and Development Centre, Agriculture and Agri-Food Canada, Summerland, British Columbia, Canada.
Etienne LordSummerland Research and Development Centre, Agriculture and Agri-Food Canada, Summerland, British Columbia, Canada.
Hélène SanfaçonSummerland Research and Development Centre, Agriculture and Agri-Food Canada, Summerland, British Columbia, Canada.ORCID 0000-0003-3807-3590
Agriculture and Agri-Food Canada · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The NIa protease of potyviruses is a chymotrypsin-like cysteine protease related to the picornavirus 3C protease. It is also a multifunctional protein known to play multiple roles during virus infection. Picornavirus 3C proteases cleave hundreds of host proteins to facilitate virus infection. However, whether or not potyvirus NIa proteases cleave plant proteins has so far not been tested. Regular expression search using the cleavage site consensus sequence [EQN]xVxH[QE]/[SGTA] for the plum pox virus (PPV) protease identified 90 to 94 putative cleavage events in the proteomes of Prunus persica (a crop severely affected by PPV), Arabidopsis thaliana, and Nicotiana benthamiana (two experimental hosts).

Indexed as

Amino Acid SequenceArabidopsisConsensus SequenceEndopeptidasesHost-Pathogen InteractionsPlant DiseasesPlant ProteinsPotyvirusProteolysisPrunus persicaRecombinant ProteinsSubstrate SpecificityViral ProteinsEndopeptidasesnuclear inclusion protein a, mosaic virusesPlant ProteinsRecombinant ProteinsViral Proteinsplant virusesplant-virus interactionplum pox viruspotyvirusproteases

Identifiers

PMID34757836
PMCPMC8791256
OpenAlexW3213710643

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.