Evidence map›Paper›PMID 34757833›Full record

ArticleJournal of clinical microbiology2022

Multicenter Clinical Evaluation of ETEST Plazomicin (PLZ) for Susceptibility Testing of Enterobacterales.

Laurine S Blanchard, Alex Van Belkum, Dominique Dechaume, Thomas P Armstrong, Christopher L Emery, Yun X Ying, Michael Kresken, Marion Pompilio, Diane Halimi, Gilles Zambardi

Open access · hybridAbstract readMulticenter Study
In one paragraph

Article in Journal of clinical microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.3field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
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  6. Article
  7. Novel Antimicrobial Agents for Gram-Negative Pathogens.Antibiotics (Basel, Switzerland) · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 3 countries.

Laurine S BlanchardbioMérieux SA, Marcy l'Etoile, France.ORCID 0000-0002-5087-7500
Alex Van BelkumbioMérieux, SA., La Balme-les-Grottes, France.
Dominique DechaumebioMérieux, SA., La Balme-les-Grottes, France.
Thomas P ArmstrongbioMérieux Inc., Hazelwood, Missouri, USA.
Christopher L EmeryIndiana University School of Medicine, Indianapolis, Indiana, USA.
Yun X YingQuest Diagnostics, Lewisville, Texas, USA.
Michael KreskenAntiinfectives Intelligence GmbH, Cologne, Germany.
Marion PompiliobioMérieux, SA., La Balme-les-Grottes, France.
Diane HalimibioMérieux, SA., La Balme-les-Grottes, France.
Gilles ZambardibioMérieux, SA., La Balme-les-Grottes, France.
bioMérieux (France) · FRbioMérieux (United States) · USFederal Office for Information Security · DEIndiana University School of MedicineQuest Diagnostics (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Plazomicin (PLZ), brand name ZEMDRI (Cipla Therapeutics), is a novel aminoglycoside antibiotic approved by the U.S. Food and Drug Administration (FDA) for treatment of complicated urinary tract infections including pyelonephritis. ETEST® is a gradient diffusion method that represents an alternative to the more laborious broth micro-dilution (BMD) method for performing antimicrobial susceptibility testing (AST). A multi-center evaluation of the performance of the new ETEST PLZ (bioMérieux) was conducted in comparison with BMD following FDA and International Standards Organization (ISO) recommendations using FDA-defined breakpoints. Clinical isolates of Enterobacterales (

Indexed as

EnterobacteriaceaePseudomonas aeruginosaAnti-Bacterial AgentsDisk Diffusion Antimicrobial TestsHumansMicrobial Sensitivity TestsSisomicinAnti-Bacterial AgentsplazomicinSisomicinantimicrobial susceptibility testingEnterobacteralesETESTgradient methodsPlazomicinplazomicin resistance mechanisms

Identifiers

PMID34757833
PMCPMC8769719
OpenAlexW3214312998

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.