Evidence map›Paper›PMID 34757823›Full record

ArticleApplied and environmental microbiology2022

Diguanylate Cyclase and Phosphodiesterase Interact To Maintain the Specificity of Cyclic di-GMP Signaling in the Regulation of Antibiotic Synthesis in Lysobacter enzymogenes.

Gaoge Xu, Lichuan Zhou, Guoliang Qian, Fengquan Liu

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Applied and environmental microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Gaoge XuInstitute of Plant Protection, Jiangsu Academy of Agricultural Sciencesgrid.454840.9, Jiangsu Key Laboratory for Food Quality and Safety-State Key Laboratory Cultivation Base, Ministry of Science and Technology, Nanjing, China.ORCID 0000-0001-5909-1718
Lichuan ZhouInformation Center, Jiangsu Academy of Agricultural Sciencesgrid.454840.9, Nanjing, China.
Guoliang QianCollege of Plant Protection, Nanjing Agricultural Universitygrid.27871.3b, Nanjing, China.
Fengquan LiuInstitute of Plant Protection, Jiangsu Academy of Agricultural Sciencesgrid.454840.9, Jiangsu Key Laboratory for Food Quality and Safety-State Key Laboratory Cultivation Base, Ministry of Science and Technology, Nanjing, China.
Jiangsu Academy of Agricultural Sciences · CNHainan University · CNNanjing Agricultural University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cyclic dimeric GMP (c-di-GMP) is a universal second messenger in bacteria. A large number of c-di-GMP-related diguanylate cyclases (DGCs), phosphodiesterases (PDEs), and effectors are responsible for the complexity and dynamics of c-di-GMP signaling. Some of these components employ various methods to avoid undesired cross talk to maintain signaling specificity. The synthesis of the antibiotic HSAF (

Indexed as

Escherichia coli ProteinsPhosphoric Diester HydrolasesAnti-Bacterial AgentsBacterial ProteinsCyclic GMPGene Expression Regulation, BacterialLysobacterPhosphorus-Oxygen LyasesAnti-Bacterial AgentsBacterial ProteinsCyclic GMPdiguanylate cyclaseEscherichia coli ProteinsPhosphoric Diester HydrolasesPhosphorus-Oxygen Lyasesc-di-GMPdiguanylate cyclaseHSAFlocal c-di-GMP signalingsignaling specificity

Identifiers

PMID34757823
PMCPMC8788788
OpenAlexW3213796580

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.