Evidence map›Paper›PMID 34757775›Full record

ArticleHypertension (Dallas, Tex. : 1979)2021

Risk-Based Intensive Blood Pressure Lowering and Prevention of Heart Failure: A SPRINT Post Hoc Analysis.

Rebecca J Molsberry, Leah Rethy, Michael C Wang, Rupal C Mehta, Donald M Lloyd-Jones, Hongyan Ning, Cora E Lewis, Clyde W Yancy, Sanjiv J Shah, Sadiya S Khan

Abstract read
In one paragraph

Article in Hypertension (Dallas, Tex. : 1979), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Hypertension in Diabetes: Numbers or Outcomes?American journal of cardiovascular drugs : drugs, devices, and other interventions · 2026
    Review
  2. Article
  3. Article
  4. Preventing new-onset heart failure: Intervening at stage A.American journal of preventive cardiology · 2023
    Review
  5. Article
  6. Review
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Rebecca J MolsberryDepartment of Epidemiology, Human Genetics, and Environmental Sciences, University of Texas Health Science Center, School of Public Health, Houston, TX (R.J.M.).
Leah RethyDepartment of Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA (L.R.).ORCID 0000-0001-8046-6895
Rupal C Mehta
Donald M Lloyd-JonesDepartment of Preventive Medicine (D.L.J., H.N., S.S.K.), Northwestern University Feinberg School of Medicine, Chicago, IL.ORCID 0000-0003-0847-6110
Hongyan NingDepartment of Preventive Medicine (D.L.J., H.N., S.S.K.), Northwestern University Feinberg School of Medicine, Chicago, IL.
Cora E LewisDivision of Cardiology, Department of Medicine (C.E.L.), Northwestern University Feinberg School of Medicine, Chicago, IL.ORCID 0000-0002-2301-5796
Sadiya S KhanDepartment of Preventive Medicine (D.L.J., H.N., S.S.K.), Northwestern University Feinberg School of Medicine, Chicago, IL.ORCID 0000-0003-0643-1859

Funding

Northwestern University Clinical and Translational Science Institute (NUCATS)UL1TR001422 · NCATS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI D'AQUILA, RICHARD · 2015 to 2023
$56.8M
Northwestern University Clinical and Translational Science Institute (NUCATS)KL2TR001424 · NCATS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI SHARMA, LEENA · 2015 to 2023
$8.1M
The Claude D. Pepper Older Americans Independence Center (OAIC) at Northwestern UniversityP30AG059988 · NIA · NORTHWESTERN UNIVERSITY AT CHICAGO · PI CELLA, DAVID · 2020 to 2024
$7.1M
Patterns of Cardiopulmonary health across the life courseR01HL159250 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI KHAN, SADIYA SANA · 2021 to 2025
$3.5M
A self-regulation approach to diabetes adherence into emerging adulthoodR01DK092939 · NIDDK · UNIVERSITY OF UTAH · PI BERG, CYNTHIA A, WIEBE, DEBORAH J · 2011 to 2015
$2.7M
CHIcago Center for Accelerating nextGen Omics, deep phenotyping, and data science in Heart Failure (CHICAGO-HF)U01HL160279 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Sadiya Sana Khan, Laura J Rasmussen-Torvik · 2021 to 2026
$1.8M
Pathogenesis of Heart Failure with Preserved Ejection Fraction in Chronic Kidney DiseaseK23HL150236 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI MEHTA, RUPAL · 2021 to 2025
$1000k
NCATS NIH HHS KL2 TR001424NCATS NIH HHS UL1 TR001422NHLBI NIH HHS K23 HL150236NHLBI NIH HHS R01 HL159250NHLBI NIH HHS U01 HL160279NIA NIH HHS P30 AG059988NIDDK NIH HHS R01 DK092939
6 · The paper itself

Abstract

[Figure: see text].

Indexed as

AgedAntihypertensive AgentsBlood PressureFemaleHeart FailureHumansIncidenceMaleMiddle AgedModels, CardiovascularRisk AssessmentRisk FactorsTreatment OutcomeAntihypertensive Agentsblood pressurecardiovascular diseasesgoalsproportional hazards modelsrisk factors

Identifiers

PMID34757775
PMCPMC8917941

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.