Evidence map›Paper›PMID 34757774›Full record

ArticleHypertension (Dallas, Tex. : 1979)2021

Noninvasive Biomarkers for Cardiovascular Dysfunction Programmed in Male Offspring of Adverse Pregnancy.

Rama Lakshman, Ana-Mishel Spiroski, Lauren B McIver, Michael P Murphy, Dino A Giussani

Open access · hybridAbstract read
In one paragraph

Article in Hypertension (Dallas, Tex. : 1979), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Guidelines for assessing maternal cardiovascular physiology during pregnancy and postpartum.American journal of physiology. Heart and circulatory physiology · 2024
    Guideline
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Rama Lakshman *Department of Physiology, Development and Neuroscience (R.L., A.-M.S., L.B.M., D.A.G.), University of Cambridge, United Kingdom.
Ana-Mishel Spiroski *Department of Physiology, Development and Neuroscience (R.L., A.-M.S., L.B.M., D.A.G.), University of Cambridge, United Kingdom.ORCID 0000-0002-8584-8048
Lauren B McIverDepartment of Physiology, Development and Neuroscience (R.L., A.-M.S., L.B.M., D.A.G.), University of Cambridge, United Kingdom.
Michael P MurphyMRC Mitochondria Biology Unit (M.P.M.), University of Cambridge, United Kingdom.
Dino A GiussaniDepartment of Physiology, Development and Neuroscience (R.L., A.-M.S., L.B.M., D.A.G.), University of Cambridge, United Kingdom.ORCID 0000-0002-1308-1204
MACOM (United States) · USMRC Epidemiology Unit · GB

Funding

British Heart Foundation PG/14/5/30547British Heart Foundation RG/17/8/32924Medical Research Council MC_U105663142Wellcome Trust 110158/Z/15/ZWellcome Trust 110159Wellcome Trust 110159/A/15/Z
6 · The paper itself

Abstract

[Figure: see text].

Indexed as

AnimalsAntioxidantsBiomarkersBlood PressureFemaleHeart RateHypoxiaMaleOrganophosphorus CompoundsOxidative StressPregnancyPrenatal Exposure Delayed EffectsRatsRats, WistarUbiquinoneAntioxidantsBiomarkersmitoquinoneOrganophosphorus CompoundsUbiquinonebiomarkerscardiovascular diseasesfetal hypoxiaoxidative stresspregnancy

Identifiers

PMID34757774
PMCPMC8577293
OpenAlexW3200745836

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.