Evidence map›Paper›PMID 34757566›Full record

ArticleThe international journal of cardiovascular imaging2022

Using deep learning method to identify left ventricular hypertrophy on echocardiography.

Xiang Yu, Xinxia Yao, Bifeng Wu, Hong Zhou, Shudong Xia, Wenwen Su, Yuanyuan Wu, Xiaoye Zheng

Open access · hybridAbstract read
In one paragraph

Article in The international journal of cardiovascular imaging, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
3.1field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Xiang YuDepartment of Cardiology, The Fourth Affiliated Hospital, School of Medicine, Zhejiang University, N1 Shangcheng Avenue, Yiwu, 322000, China.
Xinxia YaoKey Laboratory for Biomedical Engineering of Ministry of Education, Zhejiang University, Zheda Avenue, Hangzhou, 310027, China.
Bifeng WuDepartment of Cardiology, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, 310006, China.
Hong ZhouKey Laboratory for Biomedical Engineering of Ministry of Education, Zhejiang University, Zheda Avenue, Hangzhou, 310027, China. Zhouhong_zju@126.com.
Shudong XiaDepartment of Cardiology, The Fourth Affiliated Hospital, School of Medicine, Zhejiang University, N1 Shangcheng Avenue, Yiwu, 322000, China. shystone@zju.edu.cn.ORCID http://orcid.org/0000-0001-6228-5783
Wenwen SuDepartment of Cardiology, The Fourth Affiliated Hospital, School of Medicine, Zhejiang University, N1 Shangcheng Avenue, Yiwu, 322000, China.
Yuanyuan WuDepartment of Cardiology, The Fourth Affiliated Hospital, School of Medicine, Zhejiang University, N1 Shangcheng Avenue, Yiwu, 322000, China.
Xiaoye ZhengDepartment of Cardiology, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, 310006, China.
Zhejiang University · CNMinistry of Education · NZThe Fourth People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLeft ventricular hypertrophy (LVH) is an independent prognostic factor for cardiovascular events and it can be detected by echocardiography in the early stage. In this study, we aim to develop a semi-automatic diagnostic network based on deep learning algorithms to detect LVH.

methodsWe retrospectively collected 1610 transthoracic echocardiograms, included 724 patients [189 hypertensive heart disease (HHD), 218 hypertrophic cardiomyopathy (HCM), and 58 cardiac amyloidosis (CA), along with 259 controls]. The diagnosis of LVH was defined by two experienced clinicians. For the deep learning architecture, we introduced ResNet and U-net++ to complete classification and segmentation tasks respectively. The models were trained and validated independently. Then, we connected the best-performing models to form the final framework and tested its capabilities.

resultsIn terms of individual networks, the view classification model produced AUC = 1.0. The AUC of the LVH detection model was 0.98 (95% CI 0.94-0.99), with corresponding sensitivity and specificity of 94.0% (95% CI 85.3-98.7%) and 91.6% (95% CI 84.6-96.1%) respectively. For etiology identification, the independent model yielded good results with AUC = 0.90 (95% CI 0.82-0.95) for HCM, AUC = 0.94 (95% CI 0.88-0.98) for CA, and AUC = 0.88 (95% CI 0.80-0.93) for HHD. Finally, our final integrated framework automatically classified four conditions (Normal, HCM, CA, and HHD), which achieved an average of AUC 0.91, with an average sensitivity and specificity of 83.7% and 90.0%.

conclusionDeep learning architecture has the ability to detect LVH and even distinguish the latent etiology of LVH.

Indexed as

Deep learningEchocardiographyLeft ventricular hypertrophy

Identifiers

PMID34757566
PMCPMC11130004
OpenAlexW3213224457

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LicenceCC BY
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.