Evidence map›Paper›PMID 34757552›Full record

ArticleNeurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology2022

Down syndrome: the aggravation of COVID-19 may be partially justified by the expression of TMPRSS2.

Victor Gustavo Oliveira Evangelho, Murilo Lamim Bello, Helena Carla Castro, Marcia Rodrigues Amorim

Abstract readLetterComment
PubMed Full text at PMC Publisher
In one paragraph

Article in Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Victor Gustavo Oliveira EvangelhoPós-Graduação Em Ciências E Biotecnologia, Universidade Federal Fluminense, Niterói, Rio de Janeiro, Brazil.ORCID https://orcid.org/0000-0002-0560-0115
Murilo Lamim BelloLaboratório de Planejamento Farmacêutico E Simulação Computacional, Departamento de Fármacos E Medicamentos, Universidade Federal Do Rio de Janeiro, Rio de Janeiro, Brazil.ORCID https://orcid.org/0000-0003-0860-870X
Helena Carla CastroLaboratório de Antibiótico, Bioquímica, Ensino E Modelagem Molecular, Instituto de Biologia, Universidade Federal Fluminense, Niterói, Rio de Janeiro, Brazil.ORCID https://orcid.org/0000-0001-5283-1541
Marcia Rodrigues AmorimLaboratório de Genética Humana, Instituto de Biologia, Universidade Federal Fluminense, Campus do Gragoatá, Bloco M, São Domingos, Niterói, Rio de Janeiro, RJ, CEP 24201-201, Brazil. marciaamorim@id.uff.br.ORCID https://orcid.org/0000-0002-0528-0377

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

COVID-19Down SyndromeHumansSARS-CoV-2Serine EndopeptidasesSerine EndopeptidasesTMPRSS2 protein, human

Identifiers

PMID34757552
PMCPMC8579173

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.