Evidence map›Paper›PMID 34757544›Full record

ArticleNano convergence2021

Metal complexation-mediated stable and biocompatible nanoformulation of clinically approved near-infrared absorber for improved tumor targeting and photonic theranostics.

Yong-Deok Lee, Hyeon Jeong Shin, Jounghyun Yoo, Gayoung Kim, Min-Kyoung Kang, Jae Jun Lee, Joona Bang, Jin-Kyoung Yang, Sehoon Kim

Open access · diamondAbstract read
In one paragraph

Article in Nano convergence, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
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  10. Antioxidant, Enzyme, and HAntioxidants (Basel, Switzerland) · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Yong-Deok Lee *Center for Theragnosis, Korea Institute of Science and Technology, Seoul, 02792, Republic of Korea.
Hyeon Jeong Shin *Center for Theragnosis, Korea Institute of Science and Technology, Seoul, 02792, Republic of Korea.
Jounghyun Yoo *Center for Theragnosis, Korea Institute of Science and Technology, Seoul, 02792, Republic of Korea.
Gayoung KimCenter for Theragnosis, Korea Institute of Science and Technology, Seoul, 02792, Republic of Korea.
Min-Kyoung KangLaboratory Animal Center, KBIO Osong Medical Innovation Foundation, Osong, 28160, Republic of Korea.
Jae Jun LeeLaboratory Animal Center, KBIO Osong Medical Innovation Foundation, Osong, 28160, Republic of Korea.
Joona BangDepartment of Chemical and Biological Engineering, Korea University, Seoul, 02841, Republic of Korea. joona@korea.ac.kr.
Jin-Kyoung YangCenter for Theragnosis, Korea Institute of Science and Technology, Seoul, 02792, Republic of Korea. yjk0627@kist.re.kr.
Sehoon KimCenter for Theragnosis, Korea Institute of Science and Technology, Seoul, 02792, Republic of Korea. sehoonkim@kist.re.kr.
Korea Institute of Science and Technology · KRKorea University · KROsong Medical Innovation Foundation · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Indocyanine green (ICG) is a clinically approved dye that has shown great promise as a phototheranostic material with fluorescent, photoacoustic and photothermal responses in the near-infrared region. However, it has certain limitations, such as poor photostability and non-specific binding to serum proteins, subjected to rapid clearance and decreased theranostic efficacy in vivo. This study reports stable and biocompatible nanoparticles of ICG (ICG-Fe NPs) where ICG is electrostatically complexed with an endogenously abundant metal ion (Fe

Indexed as

Dual-modal imagingIndocyanine greenMetal complexPhotothermal therapyTheranostics

Identifiers

PMID34757544
PMCPMC8581101
OpenAlexW3211401465

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.