Evidence map›Paper›PMID 34757511›Full record

ArticleJournal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract2022

A Propensity-Matched Analysis of the Postoperative Venous Thromboembolism Rate After Pancreatoduodenectomy Based on Operative Approach.

Jonathan J Hue, Mohamedraed Elshami, Michael J Beckman, Michael R Driedger, Luke D Rothermel, Jeffrey M Hardacre, John B Ammori, Jordan M Winter, Lee M Ocuin

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In one paragraph

Article in Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.5field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Jonathan J HueDepartment of Surgery, Division of Surgical Oncology, University Hospitals Cleveland Medical Center, 11000 Euclid Avenue, Lakeside 7013, Cleveland, OH, 44106, USA.
Mohamedraed ElshamiDepartment of Surgery, Division of Surgical Oncology, University Hospitals Cleveland Medical Center, 11000 Euclid Avenue, Lakeside 7013, Cleveland, OH, 44106, USA.
Michael J BeckmanDepartment of Surgery, Division of Hepatobiliary and Pancreatic Surgery, Atrium Health, Charlotte, NC, USA.
Michael R DriedgerDepartment of Surgery, Division of Hepatobiliary and Pancreatic Surgery, Atrium Health, Charlotte, NC, USA.
Luke D RothermelDepartment of Surgery, Division of Surgical Oncology, University Hospitals Cleveland Medical Center, 11000 Euclid Avenue, Lakeside 7013, Cleveland, OH, 44106, USA.
Jeffrey M HardacreDepartment of Surgery, Division of Surgical Oncology, University Hospitals Cleveland Medical Center, 11000 Euclid Avenue, Lakeside 7013, Cleveland, OH, 44106, USA.
John B AmmoriDepartment of Surgery, Division of Surgical Oncology, University Hospitals Cleveland Medical Center, 11000 Euclid Avenue, Lakeside 7013, Cleveland, OH, 44106, USA.
Jordan M WinterDepartment of Surgery, Division of Surgical Oncology, University Hospitals Cleveland Medical Center, 11000 Euclid Avenue, Lakeside 7013, Cleveland, OH, 44106, USA.
Lee M OcuinDepartment of Surgery, Division of Surgical Oncology, University Hospitals Cleveland Medical Center, 11000 Euclid Avenue, Lakeside 7013, Cleveland, OH, 44106, USA. lee.ocuin@UHhospitals.org.ORCID http://orcid.org/0000-0003-3341-9521
University Hospitals of Cleveland · USAtrium Medical Cente · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe use of minimally invasive approaches for pancreatoduodenectomy has increased in recent years, but the risk of postoperative VTE is undefined. We aimed to compare venous thromboembolism (VTE) rates after open and minimally invasive pancreatoduodenectomy using an administrative dataset.

methodsPatients who underwent pancreatoduodenectomy within the National Surgical Quality Improvement Program targeted pancreatectomy database (2016-2018) were identified. VTE was compared between patients who underwent open or minimally invasive pancreatoduodenectomy directly and after propensity score matching 1:1 for demographics, comorbidities, and peri-/intra-operative factors.

resultsA total of 12,227 patients underwent pancreatoduodenectomy during the study period (open: n = 11,217; minimally invasive: n = 1010). Before matching, the VTE rate was higher among patients who underwent minimally invasive pancreatoduodenectomy (5.2% vs. 3.8%, p = 0.033), and minimally invasive resection was independently associated with VTE (OR = 1.46, 95%CI = 1.09-2.06). After matching, there were 916 patients per group without differences in demographics or comorbidities. Patients who underwent minimally invasive pancreatoduodenectomy had longer median operative times (422 vs. 348 min). The VTE rate remained higher following minimally invasive pancreatoduodenectomy after matching (5.1% vs. 2.9%, p = 0.018), mainly driven by a higher DVT rate (3.9% vs. 1.7%, p = 0.005).

conclusionsMinimally invasive pancreatoduodenectomy is associated with a higher postoperative VTE rate compared to open pancreatoduodenectomy.

Indexed as

Pulmonary EmbolismVenous ThromboembolismHumansPancreaticoduodenectomyPostoperative ComplicationsPropensity ScoreRisk FactorsDeep vein thrombosisMinimally invasive surgeryPancreatoduodenectomyPulmonary embolismVenous thromboembolism

Identifiers

PMID34757511
OpenAlexW3212506934

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.