ArticleJournal of patient-reported outcomes2021
Health-related quality of life for adults living with hepatitis B in the United States: a qualitative assessment.
Article in Journal of patient-reported outcomes, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
28 citing papers in PubMed, 1 synthesis or guideline pooled it, 41 citations in OpenAlex.
- A Systematic Review of the Impact of Resveratrol on Viral Hepatitis and Chronic Viral Hepatitis-related Hepatocellular Carcinoma.Current molecular medicine · 2025Pooled it
- Health-related quality of life in adults with hepatitis B in sub-Saharan Africa: the added burden of HIV co-infection.BMC infectious diseases · 2026Observational
- Prevalence and risk factors for hepatitis B virus infection among expectant mothers in Jirapa Municipality, Upper West Region, Ghana: a facility-based cross-sectional study.BMC public health · 2026Article
- Chronic liver disease questionnaire analysis in pregnant women with hepatitis B: a prospective study.BMC pregnancy and childbirth · 2026Article
- Breaking the stigma: the role of family support in hepatitis B management from a public health education perspective.Frontiers in public health · 2026Review
- Time for a globally unified chronic HBV terminology?JHEP reports : innovation in hepatology · 2025Review
- Meta-analysis of factors associated with the incidence of comorbid depression and anxiety in patients with chronic hepatitis B.World journal of psychiatry · 2025Article
- Psychiatric symptoms and necroinflammatory activity in chronic hepatitis B: a cross-sectional study.BMC infectious diseases · 2025Article
- Envisioning a Multidisciplinary HBV Cure Research Agenda.Current HIV/AIDS reports · 2025Review
- Patient and public health perspectives to inform expansion of hepatitis B treatment guidelines.The lancet. Gastroenterology & hepatology · 2025Review
- A Qualitative Exploration of Family and Marital Challenges Faced by the Hepatitis-B Positive Patients and Their Partners in Central India.Indian journal of community medicine : official publication of Indian Association of Preventive & Social Medicine · 2025Article
- Association between resolved hepatitis B virus infection and depression in American adults : a cross-sectional study.Scientific reports · 2025Article
- EFFECTIVENESS OF HERBAL AND CONVENTIONAL MANAGEMENT INTERVENTIONS OF HEPATITIS B VIRUS.African journal of infectious diseases · 2025Article
- Beyond the liver: well-being as the bridge between fatigue and quality of life in chronic hepatitis B patients.Frontiers in public health · 2025Article
- Article
- A conceptual model for chronic hepatitis B and content validity of the Hepatitis B Quality of Life (HBQOL) instrument.Journal of patient-reported outcomes · 2024Review
- Clinical effectiveness of entecavir versus tenofovir disoproxil fumarate tablets in chronic hepatitis B treatment.American journal of translational research · 2024Article
- Quality of life of people living with chronic hepatitis B: The role of social support system.PLOS global public health · 2024Article
- Symptoms of Liver Disease During Tenofovir Therapy With or Without Peginterferon: Results from the Hepatitis B Research Network Immune Active Trial.Digestive diseases and sciences · 2023Article
- Change in Health-Related Quality of Life in Youth with Chronic Hepatitis B Living in North America: A 5-Year Cohort Study.Journal of pediatric gastroenterology and nutrition · 2023Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIn 2019, an estimated 296 million people were living with chronic hepatitis B virus (HBV) globally with approximately 2.4 million living within the United States. Those living with HBV require years if not decades of regular monitoring to prevent liver complications from occurring. The aim of this study was to explore the working conceptual framework of health related quality of life (HRQL) for those living with chronic HBV through qualitative analysis.
methodsData were collected by in-depth telephone interviews conducted in 2019 using purposeful sampling as part of a disease understanding assessment on the HBV patient experience within the United States. A directed content analysis approach was utilized by creation of a codebook to guide the organization of data, codes were developed by review of the literature (a priori) and through line-by-line reading of a subsample of queries. All transcripts were analyzed by at least two members of the study team and intercoder reliability was assessed using Dedoose software.
findingsA sample of 19 individuals living with chronic HBV were included within this study. Themes identified from transcripts noted the significant overlap between the reported experience of HBV and constructs within the HRQL model. The psychological impact of chronic HBV on study participants' HRQL overall was considerable and contributed to depression, anxiety, homelessness, drug use, and incarceration.
conclusionOur analysis supports the hypothesis that HBV impacts HRQL and often negatively affects emotional health. Our findings suggest that it would be beneficial to include HRQL assessment in the medical management of HBV, so that interventions can focus on reducing the burden of disease and improving quality of life for those living with HBV.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.