Evidence map›Paper›PMID 34757371›Full record

ArticleJournal of materials chemistry. B2021

Synthesis and characterization of a novel pH-responsive drug-releasing nanocomposite hydrogel for skin cancer therapy and wound healing.

Andrea Gonsalves, Pranjali Tambe, Duong Le, Dheeraj Thakore, Aniket S Wadajkar, Jian Yang, Kytai T Nguyen, Jyothi U Menon

Open access · greenAbstract read
In one paragraph

Article in Journal of materials chemistry. B, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 46 citations in OpenAlex.

  1. Review
  2. A Monolithic Janus Hydrogel Pressure Sensor for Wearable Motion and Physiological Monitoring.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  3. Review
  4. Article
  5. Review
  6. Review
  7. Review
  8. Article
  9. Review
  10. Review
  11. Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Andrea GonsalvesDepartment of Biomedical and Pharmaceutical Sciences, College of Pharmacy, University of Rhode Island, 7 Greenhouse Road, Kingston, RI 02881, USA. jmenon@uri.edu.
Pranjali TambeDepartment of Bioengineering, University of Texas at Arlington, Arlington, TX 76019, USA.
Duong LeDepartment of Biomedical and Pharmaceutical Sciences, College of Pharmacy, University of Rhode Island, 7 Greenhouse Road, Kingston, RI 02881, USA. jmenon@uri.edu.
Dheeraj ThakoreDepartment of Bioengineering, University of Texas at Arlington, Arlington, TX 76019, USA.
Aniket S WadajkarDepartment of Bioengineering, University of Texas at Arlington, Arlington, TX 76019, USA.
Jian YangDepartment of Biomedical Engineering, Pennsylvania State University, University Park, PA 16802, USA.
Kytai T NguyenDepartment of Bioengineering, University of Texas at Arlington, Arlington, TX 76019, USA.
Jyothi U MenonDepartment of Biomedical and Pharmaceutical Sciences, College of Pharmacy, University of Rhode Island, 7 Greenhouse Road, Kingston, RI 02881, USA. jmenon@uri.edu.ORCID 0000-0002-0762-3513
The University of Texas at Arlington · USUniversity of Rhode Island · USPennsylvania State University · USUniversity of Maryland, Baltimore · US

Funding

Training CoreP20GM103430 · NIGMS · UNIVERSITY OF RHODE ISLAND · PI Bongsup P Cho · 2012 to 2026
$63.6M
Citrate Metabonegenic Regulation for the next Generation of Orthopedic Biomaterial DesignR01AR072731 · NIAMS · PENNSYLVANIA STATE UNIVERSITY, THE · PI YANG, JIAN · 2018 to 2022
$1.7M
Synergistic Upregulation of EpoR /RopE NPs for Enhancing Effective Angiogenesis to treat PADR15HL156076 · NHLBI · UNIVERSITY OF TEXAS ARLINGTON · PI NGUYEN, KYTAI TRUONG · 2021 to 2021
$443k
NHLBI NIH HHS R15 HL156076NIAMS NIH HHS R01 AR072731NIGMS NIH HHS P20 GM103430
6 · The paper itself

Abstract

Local skin cancer recurrence occurs in ∼12% of the patients post-surgery due to persistent growth of residual cancer cells. Wound infection is another significant complication following surgery. We report a novel

Indexed as

Anti-Bacterial AgentsAntineoplastic AgentsBiocompatible MaterialsCell Line, TumorCell SurvivalChitosanDrug Delivery SystemsFluorouracilHumansHydrogelsHydrogen-Ion ConcentrationNanocompositesPolyethylene GlycolsSkin NeoplasmsWound HealingAnti-Bacterial AgentsAntineoplastic AgentsBiocompatible MaterialsChitosanFluorouracilHydrogelspolyethylene glycol maleate citratePolyethylene Glycols

Identifiers

PMID34757371
PMCPMC8725646
OpenAlexW3212846571

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.