Evidence map›Paper›PMID 34756836›Full record

ArticleThe Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases

Leprosy morbidity and mortality in Brazil: 2008-2018.

Camila Botelho Miguel, Patrício Barbosa da Mota, Breno Oliveira Afonso, Ferdinando Agostinho, Rodrigo Anselmo Cazzaniga, Melissa Carvalho Martins de Abreu, Carlo José Freire Oliveira, Wellington Francisco Rodrigues

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.2field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 22 citations in OpenAlex.

  1. Temporal trend and factors associated with physical disability due to leprosyl: a time series study, Brazil, 2014-2023.Epidemiologia e servicos de saude : revista do Sistema Unico de Saude do Brasil · 2026
    Article
  2. Article
  3. Article
  4. Mitochondria inInternational journal of molecular sciences · 2022
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Camila Botelho MiguelUniversity Centre of Mineiros-UNIFIMES, Mineiros, GO, Brazil; Laboratory of Immunology and Bioinformatics, Institute of Biological and Natural Sciences, Federal University of Triangulo Mineiro, Uberaba, MG, Brazil.
Patrício Barbosa da MotaUniversity Centre of Mineiros-UNIFIMES, Mineiros, GO, Brazil.
Breno Oliveira AfonsoInstitute of Health Sciences, Federal University of Triângulo Mineiro, Uberaba, MG, Brazil.
Ferdinando AgostinhoLaboratory of Immunology and Bioinformatics, Institute of Biological and Natural Sciences, Federal University of Triangulo Mineiro, Uberaba, MG, Brazil.
Rodrigo Anselmo CazzanigaLaboratory of Immunology and Bioinformatics, Institute of Biological and Natural Sciences, Federal University of Triangulo Mineiro, Uberaba, MG, Brazil.
Melissa Carvalho Martins de AbreuUniversity Centre of Mineiros-UNIFIMES, Mineiros, GO, Brazil.
Carlo José Freire OliveiraLaboratory of Immunology and Bioinformatics, Institute of Biological and Natural Sciences, Federal University of Triangulo Mineiro, Uberaba, MG, Brazil. Electronic address: carlo.oliveira@uftm.edu.br.
Wellington Francisco RodriguesPostgraduate Course in Health Sciences, Federal University of Triângulo Mineiro, Uberaba, MG, Brazil.
Universidade Federal do Triângulo Mineiro · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionLeprosy is an infectious disease caused by Mycobacterium leprae. This study aimed to understand the distribution and impact of Hansen's disease in different regions of Brazil and the outcome of cases in recent years. METHODOLOGY: An ecological study was conducted throughout the Brazilian territory for 11 years (2008-2018). The mortality rates, new cases of the disease, and proportion of physical disability and cure were assessed. Data were obtained using DATASUS. GraphPad Excel and "Prisma" programs were used for tabulation and data processing. To present an accurate perspective from all regions, the data were normalized according to the population.

resultsOverall, the results demonstrated a significant reduction in the number of leprosy cases in Brazil over the last decade (p < 0.05). North and Midwest regions showed higher mortality rates standardized by age (p < 0.05). The largest number of cases were found in Tocantins and Mato Grosso, inner states of Brazil (p < 0.05). The cure rates in the Southeast and South regions were negatively correlated with the mortality rate in these regions (p < 0.05).

conclusionsActions to control the spread and unfavorable outcomes of leprosy have been effective in the last decade in most Brazilian states. On the other hand, the states of Tocantins and Mato Grosso, in the North and Midwest regions of Brazil, need to intensify the fight against the disease. Notwithstanding, measures against leprosy should continue and be intensified in regions with greater aggravations, aiming at an effective homogeneous control of the disease.

Indexed as

LeprosyBrazilChlorhexidineHumansMorbidityMycobacterium lepraeChlorhexidineBrazilEpidemiologyLeprosy

Identifiers

PMID34756836
PMCPMC9392197
OpenAlexW3208224674

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.