Evidence map›Paper›PMID 34756769›Full record

ArticleVaccine2021

The economic burden of rotavirus hospitalization among children < 5 years of age in selected hospitals in Bangladesh.

Sayem Ahmed, Farzana Dorin, Syed Moinuddin Satter, Abdur Razzaque Sarker, Marufa Sultana, Paul A Gastanaduy, Umesh Parashar, Jacqueline E Tate, James D Heffelfinger, Emily S Gurley and 1 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Vaccine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
0.5field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it, 13 citations in OpenAlex.

  1. Pooled it
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  3. Review
  4. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 8 countries.

Sayem Ahmedicddr,b, Dhaka, Bangladesh; Mathematical Modelling Group, Oxford University Clinical Research Unit (OUCRU), Ho Chi Minh City, Viet Nam; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, United Kingdom. Electronic address: sayem.ahmed@ndm.ox.ac.uk.
Farzana Dorinicddr,b, Dhaka, Bangladesh.
Syed Moinuddin Sattericddr,b, Dhaka, Bangladesh.
Abdur Razzaque Sarkericddr,b, Dhaka, Bangladesh; University of Strathclyde, Glasgow, Scotland, UK; Bangladesh Institute of Development Studies, Dhaka, Bangladesh.
Marufa Sultanaicddr,b, Dhaka, Bangladesh; Deakin Health Economics, School of Health and Social Development, Deakin University, Geelong, Victoria, Australia.
Paul A GastanaduyCenters for Disease Control and Prevention, Atlanta, GA, USA.
Umesh ParasharCenters for Disease Control and Prevention, Atlanta, GA, USA.
Jacqueline E TateCenters for Disease Control and Prevention, Atlanta, GA, USA.
James D Heffelfingericddr,b, Dhaka, Bangladesh; Centers for Disease Control and Prevention, Atlanta, GA, USA.
Emily S Gurleyicddr,b, Dhaka, Bangladesh; John Hopkins University, Baltimore, MD, USA.
Jahangir A M Khanicddr,b, Dhaka, Bangladesh; Karolinska Institutet, Stockholm, Sweden; School of Public Health and Community Medicine, University of Gothenburg, Gothenburg, Sweden.
Centers for Disease Control and Prevention · USInternational Centre for Diarrhoeal Disease Research · BDBangladesh Institute of Development Studies · BDDeakin University · AUJohns Hopkins University · US

Funding

CGH CDC HHS U51 GH001209Intramural CDC HHS CC999999
6 · The paper itself

Abstract

backgroundRotavirus is a common cause of severe acute gastroenteritis among young children. Estimation of the economic burden would provide informed decision about investment on prevention strategies (e.g., vaccine and/or behavior change), which has been a potential policy discussion in Bangladesh for several years.

methodsWe estimated the societal costs of children <5 years for hospitalization from rotavirus gastroenteritis (RVGE) and incidences of catastrophic health expenditure. A total of 360 children with stool specimens positive for rotavirus were included in this study from 6 tertiary hospitals (3 public and 3 private). We interviewed the caregiver of the patient and hospital staff to collect cost from patient and health facility perspectives. We estimated the economic cost considering 2015 as the reference year.

resultsThe total societal per-patient costs to treat RVGE in the public hospital were 126 USD (95% CI: 116-136) and total household costs were 161 USD (95% CI: 145-177) in private facilities. Direct costs constituted 38.1% of total household costs. The out-of-pocket payments for RVGE hospitalization was 23% of monthly income and 76% of households faced catastrophic healthcare expenditures due to this expense. The estimated total annual household treatment cost for the country was 10 million USD.

conclusionsA substantial economic burden of RVGE in Bangladesh was observed in this study. Any prevention of RVGE through cost-effective vaccination or/and behavioural change would contribute to substantial economic benefits to Bangladesh.

Indexed as

RotavirusRotavirus InfectionsRotavirus VaccinesBangladeshChildChild, PreschoolCost of IllnessFinancial StressHospitalizationHospitalsHumansInfantRotavirus VaccinesBangladeshCatastrophic health expenditureCosts-of-illnessDiarrheaEconomic burdenRotavirus gastroenteritis

Identifiers

PMID34756769
PMCPMC11756831
OpenAlexW3210186978

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.