ArticleMemorias do Instituto Oswaldo Cruz2021
Epidemiology of paracoccidioidomycosis in Venezuela: a retrospective study from 1954 to 2019.
Article in Memorias do Instituto Oswaldo Cruz, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
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Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Paracoccidioidomycosis in Childhood and Adolescence: Clinical-Epidemiological Review of South American Cases (1970-2023).Mycopathologia · 2025Pooled it
- Paracoccidioidomycosis in the 21st century: Challenges and milestones.PLoS neglected tropical diseases · 2026Review
- Comparison between PCR-RFLP and sequencing techniques in the analysis of Paracoccidioides spp. biodiversity: limitations and insights into species and variant differentiation.Mycopathologia · 2024Article
- Paracoccidioidomycosis presenting as a cecal lesion mimicking cholangiocarcinoma: a case report of unusual intestinal manifestation.Revista do Instituto de Medicina Tropical de Sao Paulo · 2024Article
- Make the diagnosis - Second partBiomedica : revista del Instituto Nacional de Salud · 2023Article
- Clinical and Demographic Features of Paracoccidioidomycosis in Argentina: A Multicenter Study Analysis of 466 Cases.Journal of fungi (Basel, Switzerland) · 2023Article
- Oral paracoccidioidomycosis: a retrospective study of 95 cases from a single center and literature review.Medicina oral, patologia oral y cirugia bucal · 2023Review
- Human Airway Epithelium Responses to Invasive Fungal Infections: A Critical Partner in Innate Immunity.Journal of fungi (Basel, Switzerland) · 2022Review
- Paracoccidioidomycosis: What We Know and What Is New in Epidemiology, Diagnosis, and Treatment.Journal of fungi (Basel, Switzerland) · 2022Review
Corrections and comments
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Authors and funding
7 authors.
Funding
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Abstract
backgroundParacoccidioidomycosis (PCM) is a systemic mycosis endemic to Latin America. Etiological agents are Paracoccidioides species that diverge phylogenetically throughout South America.
objectivesThis study aimed to document the epidemiology of PCM in Venezuela.
methodsWe have performed a retrospective cross-sectional descriptive study in 31,081 clinical records of patients from two reference centres during 65 years (1954-2019).
findingsPCM diagnosis was confirmed in 745 patients. Chronic PCM was the most prevalent form (90.06% cases); 80.67% were male and the most affected age range was 41-60. Farming and construction were the most prevalent occupation and Miranda State had a higher prevalence. Lung and skin were the most affected organs, followed by oral manifestations. Direct examination, culture and serology showed a high sensibility, and no statistical difference was observed among the diagnostic tools. Out of 17 Paracoccidioides isolates genotyped from Venezuela, one was typed as Paracoccidioides americana and 16 as Paracoccidioides venezuelensis. MAIN
conclusionsClinical manifestations observed, information about the epidemiology and molecular profile is essential not only for diagnosis but also for understanding therapeutic responses to mycotic drugs and prognosis. Therefore, it is necessary to sequence all positive isolated strains in order to confirm the dominance of P. venezuelensis in Venezuela.
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