Evidence map›Paper›PMID 34755765›Full record

ArticleActa cirurgica brasileira2021

Morphological, biochemical and histological effects of aqueous extracts of peanut (Arachis hypogaea) on swiss mice in different diets.

Thárcia Kiara Beserra de Oliveira, Josivanda Palmeira Gomes, Paulo Roberto da Silva Júnior, Amelia Ruth Nascimento Lima, Ana Janaina Jeanine Martins de Lemos Jordão, Katharina Rodrigues de Lima Porto Ramos, Joelmir Lucena Veiga da Silva, Chirlaine Cristine Gonçalves

Open access · goldAbstract read
In one paragraph

Article in Acta cirurgica brasileira, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Thárcia Kiara Beserra de OliveiraDVM, PhD. Postgraduate Program of Agricultural Engeneering - Department of Technology and Natural Resources - Universidade Federal de Campina Grande (UFCG) - Campina Grande (PB), Brazil. Assistant Professor. Division of Surgical Skills - Surgical Technique I and II - Faculdade de Medicina de Olinda (FMO) - Olinda (PE), Brazil.ORCID http://orcid.org/0000-0001-6352-7254
Josivanda Palmeira GomesPhD. Postgraduate Program of Agricultural Engeneering - Department of Technology and Natural Resources - Universidade Federal de Campina Grande (UFCG) - Campina Grande (PB), Brazil.ORCID http://orcid.org/0000-0002-2047-986X
Paulo Roberto da Silva JúniorGraduate student. Department of Medicine - Centro Universitário Unifacisa - Faculdade de Ciências Médicas de Campina Grande - Campina Grande (PB), Brazil.ORCID http://orcid.org/0000-0002-8488-0927
Amelia Ruth Nascimento LimaMSc student. Department of Natural Sciences and Biotechnology - Universidade Federal de Campina Grande (UFCG) - Campina Grande (PB), Brazil.ORCID http://orcid.org/0000-0002-3565-5125
Ana Janaina Jeanine Martins de Lemos JordãoPhD. Department of Animal Bioscience - Universidade Federal Rural de Pernambuco (UFRPE) - Recife (PE), Brazil.ORCID http://orcid.org/0000-0002-3640-1450
Katharina Rodrigues de Lima Porto RamosFellow PhD degree. Postgraduate Program of Processing Engeneering - Department of Pharmaceutical Sciences - Universidade Federal de Campina Grande (UFCG) - Campina Grande (PB), Brazil.ORCID http://orcid.org/0000-0001-7747-144X
Joelmir Lucena Veiga da SilvaPhD. Department of Natural and Synthetic Bioactive Products - Universidade Federal da Paraíba (UFPB) - João Pessoa (PB), Brazil.ORCID http://orcid.org/0000-0001-5722-0213
Chirlaine Cristine GonçalvesPhD. Postgraduate Program of Processing Engeneering - Department of Sciences and Technology - Universidade Federal de Campina Grande (UFCG) - Campina Grande (PB), Brazil.ORCID http://orcid.org/0000-0003-1321-3366
Universidade Federal de Campina Grande · BRUniversidade Federal da Paraíba · BRUniversidade Federal Rural de Pernambuco · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate the morphological, biochemical, and histological effects of aqueous extracts of peanut (skinless and added to 1% skin) in Swiss mice submitted to a high-fat diet.

methodsForty male Swiss mice were divided into four groups (n=10 per group): GI) normocaloric diet; GII) high-fat diet; GIII) high-fat diet + 0.5 mL of peanut extract; GIV) high-fat diet + 0.5 mL of peanut extract + 1% peanut skin. The animals were weighed weekly and euthanized after 12 weeks for histopathological and biochemical analyses. The study was approved by the Animal Use Ethics Committee.

resultsThe animals in the GIV group had higher body weight when compared to the other ones. Increase in total cholesterol in GIII, increase in blood glucose in groups GII, GIII and GIV, decrease in serum low-density lipoprotein (LDL) concentration in groups GI and GIV and increase in serum concentration of C-reactive protein in GII were seen. The presence of vacuolar fat deposits was found in animal livers from GII.

conclusionsThe extracts improved the plasma concentrations of animals that received a high-fat diet, including preventing morphological damage to liver tissue. These benefits were enhanced by the association of peanut shells with the extract.

Indexed as

ArachisDiet, High-FatAnimalsLiverMiceOverweightPlant ExtractsPlant Extracts

Identifiers

PMID34755765
PMCPMC8580511
OpenAlexW3213042928

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.