Evidence map›Paper›PMID 34755700›Full record

ArticleAsian journal of andrology

High IL-23+ cells infiltration correlates with worse clinical outcomes and abiraterone effectiveness in patients with prostate cancer.

Zheng Liu, Jun-Yu Zhang, Yun-Jie Yang, Kun Chang, Qi-Feng Wang, Yun-Yi Kong, Bo Dai

Open access · goldAbstract read
In one paragraph

Article in Asian journal of andrology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Review
  6. Review
  7. Impact of IL-23 in prostate cancer.Asian journal of andrology
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Zheng LiuDepartment of Urology, Fudan University Shanghai Cancer Center, Shanghai 200032, China.
Jun-Yu ZhangDepartment of Urology, Fudan University Shanghai Cancer Center, Shanghai 200032, China.
Yun-Jie YangDepartment of Urology, Fudan University Shanghai Cancer Center, Shanghai 200032, China.
Kun ChangDepartment of Urology, Fudan University Shanghai Cancer Center, Shanghai 200032, China.
Qi-Feng WangDepartment of Oncology, Shanghai Medical College, Fudan University, Shanghai 200032, China.
Yun-Yi KongDepartment of Oncology, Shanghai Medical College, Fudan University, Shanghai 200032, China.
Bo DaiDepartment of Urology, Fudan University Shanghai Cancer Center, Shanghai 200032, China.
Shanghai Medical College of Fudan University · CNFudan University Shanghai Cancer Center · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Individualized treatment of prostate cancer depends on an accurate stratification of patients who are sensitive to various treatments. Interleukin-23 (IL-23) was reported to play a significant role in prostate cancer. Here, we aimed to explore the clinical value of IL-23-secreting (IL-23+) cells in prostate cancer patients. We evaluated interleukin-23A (IL-23A) expression in The Cancer Genome Atlas database and retrospectively enrolled 179 treatment-naïve metastatic prostate cancer patients diagnosed in our institute between June 2012 and December 2014. IL-23

Indexed as

Interleukin-23Prostatic Neoplasms, Castration-ResistantAbiraterone AcetateAndrostenesAntineoplastic Combined Chemotherapy ProtocolsDisease-Free SurvivalHumansMaleRetrospective StudiesTreatment OutcomeabirateroneAbiraterone AcetateAndrostenesInterleukin-23abiraterone acetateinterleukin-23prognosisprostate cancer

Identifiers

PMID34755700
PMCPMC8887101
OpenAlexW3213544796

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.