Evidence map›Paper›PMID 34755664›Full record

ArticleNan fang yi ke da xue xue bao = Journal of Southern Medical University2021

[

X Wang, J Zhu, Y Gao, F Wu, Q Yang, J Tong, X Zhang, C Wang, D Wu, Z Li

Open access · greenAbstract read
In one paragraph

Article in Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 76% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

X WangGraduate School, Anhui University of Chinese Medicine, Hefei 230012, China.
J ZhuCollege of Integrated Chinese and Western Medicine, Anhui University of Chinese Medicine, Hefei 230012, China.
Y GaoGraduate School, Anhui University of Chinese Medicine, Hefei 230012, China.
F WuGraduate School, Anhui University of Chinese Medicine, Hefei 230012, China.
Q YangGraduate School, Anhui University of Chinese Medicine, Hefei 230012, China.
J TongFirst Affiliated Hospital of Anhui University of Chinese Medicine, Hefei 230031, China.
X ZhangFirst Affiliated Hospital of Anhui University of Chinese Medicine, Hefei 230031, China.
C WangInstitute of Medicine for Respiratory Disease, Anhui Academy of Chinese Medicine, Hefei 230031, China.
D WuGraduate School, Anhui University of Chinese Medicine, Hefei 230012, China.
Z LiFirst Affiliated Hospital of Anhui University of Chinese Medicine, Hefei 230031, China.
Anhui University of Traditional Chinese Medicine · CNAnhui Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate the characteristics of immune cell subsets in the lung tissues of patients with chronic obstructive pulmonary disease (COPD) and the mechanism of

methodsWe downloaded COPD-related single-cell RNA sequencing data from Gene Expression Omnibus (GEO) and identified COPD immune cell subsets using the Seurat package in the R software to construct an immune cell subsets-differential genes network. The target genes and active ingredients of

resultsA total of 18 immune-related cell subsets, including macrophages and alveolar macrophages, were identified in both COPD patients and healthy control subjects, and the patients with COPD showed significant changes the percentages of macrophages, cDC1, pDC, mast cells, T cells, and mature dendritic cells (

conclusion

Indexed as

Drugs, Chinese HerbalImmunityPulmonary Disease, Chronic ObstructiveAnimalsHumansLungNF-kappa BRatsSignal TransductionDrugs, Chinese HerbalNF-kappa Bchronic obstructive pulmonary diseaseimmune and inflammationLiuwei Buqi capsulesingle-cell RNA sequencing

Identifiers

PMID34755664
PMCPMC8586865
OpenAlexW3213737193

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.