Evidence map›Paper›PMID 34755602›Full record

ArticleeLife2021

Modeling the

Emilie Barruet, Steven M Garcia, Jake Wu, Blanca M Morales, Stanley Tamaki, Tania Moody, Jason H Pomerantz, Edward C Hsiao

Open access · goldAbstract read
In one paragraph

Article in eLife, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
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  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Emilie BarruetDivision of Plastic and Reconstructive Surgery, Departments of Surgery and Orofacial Sciences, the Program in Craniofacial Biology, and the Eli and Edythe Broad Center of Regeneration Medicine, University of California - San Francisco, San Francisco, United States.ORCID 0000-0002-4593-024X
Steven M GarciaDivision of Plastic and Reconstructive Surgery, Departments of Surgery and Orofacial Sciences, the Program in Craniofacial Biology, and the Eli and Edythe Broad Center of Regeneration Medicine, University of California - San Francisco, San Francisco, United States.ORCID 0000-0002-7833-6677
Jake WuDivision of Plastic and Reconstructive Surgery, Departments of Surgery and Orofacial Sciences, the Program in Craniofacial Biology, and the Eli and Edythe Broad Center of Regeneration Medicine, University of California - San Francisco, San Francisco, United States.
Blanca M MoralesDivision of Endocrinology and Metabolism, Department of Medicine, the Institute for Human Genetics, the Program in Craniofacial Biology, and the Eli and Edythe Broad Center of Regeneration Medicine, University of California - San Francisco, San Francisco, United States.
Stanley TamakiDivision of Plastic and Reconstructive Surgery, Departments of Surgery and Orofacial Sciences, the Program in Craniofacial Biology, and the Eli and Edythe Broad Center of Regeneration Medicine, University of California - San Francisco, San Francisco, United States.
Tania MoodyDivision of Endocrinology and Metabolism, Department of Medicine, the Institute for Human Genetics, the Program in Craniofacial Biology, and the Eli and Edythe Broad Center of Regeneration Medicine, University of California - San Francisco, San Francisco, United States.
Jason H PomerantzDivision of Plastic and Reconstructive Surgery, Departments of Surgery and Orofacial Sciences, the Program in Craniofacial Biology, and the Eli and Edythe Broad Center of Regeneration Medicine, University of California - San Francisco, San Francisco, United States.ORCID 0000-0002-5107-1883
Edward C HsiaoDivision of Endocrinology and Metabolism, Department of Medicine, the Institute for Human Genetics, the Program in Craniofacial Biology, and the Eli and Edythe Broad Center of Regeneration Medicine, University of California - San Francisco, San Francisco, United States.ORCID 0000-0001-8924-106X
University of California, San Francisco · US

Funding

Innate immune regulation of stem cells in bone formationR01AR066735 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI HSIAO, EDWARD C · 2015 to 2019
$1.8M
Regeneration and Differentiation Potential of Heterogeneous Human Satellite CellsR01AR072638 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI POMERANTZ, JASON · 2017 to 2021
$1.7M
NIAMS NIH HHS R01 AR066735NIAMS NIH HHS R01 AR072638
6 · The paper itself

Abstract

Abnormalities in skeletal muscle repair can lead to poor function and complications such as scarring or heterotopic ossification (HO). Here, we use fibrodysplasia ossificans progressiva (FOP), a disease of progressive HO caused by

Indexed as

MutationActivin Receptors, Type IAdultAnimalsFemaleHumansInduced Pluripotent Stem CellsMiceMiddle AgedMuscle Fibers, SkeletalMyositis OssificansOssification, HeterotopicSignal TransductionActivin Receptors, Type IACVR1 protein, humanACVR1cell biologyfibrodysplasia ossificans progressivav FOPheterotopic ossificationhumanhuman induced pluripotent stem cells iPSCshuman muscle stem cells hu-MuSCshuman satellite cells hu-SCsregenerative medicinestem cells

Identifiers

PMID34755602
PMCPMC8691832
OpenAlexW3211785014

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.