Evidence map›Paper›PMID 34755540›Full record

ArticleAmerican journal of physiology. Lung cellular and molecular physiology2022

Integrative analysis reveals mouse strain-dependent responses to acute ozone exposure associated with airway macrophage transcriptional activity.

Adelaide Tovar, Wesley L Crouse, Gregory J Smith, Joseph M Thomas, Benjamin P Keith, Kathryn M McFadden, Timothy P Moran, Terrence S Furey, Samir N P Kelada

Open access · greenAbstract read
In one paragraph

Article in American journal of physiology. Lung cellular and molecular physiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Evaluating the role of alveolar macrophages in tolerance to ozone.Toxicological sciences : an official journal of the Society of Toxicology · 2025
    Article
  5. Article
  6. Effects of RadioactiveInternational journal of molecular sciences · 2023
    Article
  7. Article
  8. Article
  9. A Murine Model of Ozone-induced Nonatopic Asthma from the Collaborative Cross.American journal of respiratory cell and molecular biology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Adelaide TovarDepartment of Genetics, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.ORCID 0000-0003-1699-7231
Wesley L CrouseDepartment of Genetics, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.ORCID 0000-0001-5745-4490
Gregory J SmithDepartment of Genetics, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.ORCID 0000-0002-5305-0445
Joseph M ThomasDepartment of Genetics, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.
Benjamin P KeithDepartment of Genetics, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.ORCID 0000-0003-1398-5569
Kathryn M McFaddenDepartment of Genetics, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.
Timothy P MoranDepartment of Pediatrics, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.ORCID 0000-0002-6832-9772
Terrence S FureyDepartment of Genetics, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.ORCID 0000-0001-5546-9672
Samir N P KeladaDepartment of Genetics, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.ORCID 0000-0003-2676-9232
University of North Carolina at Chapel Hill · US

Funding

UNC-CH CENTER FOR ENVIRONMENTAL HEALTH &SUSCEPTIBILITYP30ES010126 · NIEHS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Stephanie Engel · 2001 to 2026
$36.3M
TOXICOLOGYT32ES007126 · NIEHS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI ILONA JASPERS, Bernard E. Weissman · 1985 to 2026
$13.0M
Gene-Environment Interactions with Ozone in Experimental AsthmaR01ES024965 · NIEHS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI KELADA, SAMIR · 2015 to 2019
$2.2M
The role of neuropilin-2 in regulating environmental airways injuryK08ES029118 · NIEHS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI MORAN, TIMOTHY · 2019 to 2021
$635k
NIEHS NIH HHS K08 ES029118NIEHS NIH HHS P30 ES010126NIEHS NIH HHS R01 ES024965NIEHS NIH HHS T32 ES007126
6 · The paper itself

Abstract

Acute ozone (O

Indexed as

AnimalsChromatinCytokinesFemaleGene Expression RegulationInflammationLungMacrophagesMaleMiceMice, Inbred C57BLOzonePhenotypeRNA, MessengerTranscription, GeneticChromatinCytokinesOzoneRNA, Messengerairway macrophagesgene-environment interactionsmouseozonetranscriptomics

Identifiers

PMID34755540
PMCPMC8721896
OpenAlexW3213540004

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.