Evidence map›Paper›PMID 34755373›Full record

ArticleJournal of medical virology2022

Factors associated with mechanical ventilation in SARS-CoV-2 patients treated with high-flow nasal cannula oxygen and outcomes.

Xavier Leroux, Maud Schock, Olivier Augereau, Henry Lessire, Charles Bouterra, Lounis Belilita, Pierre Rerat, Antonio Alvarez, Martin Martinot, Victor Gerber

Open access · greenAbstract read
In one paragraph

Article in Journal of medical virology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Xavier LerouxService de réanimation médicale,  Hôpital Pasteur de Colmar, Colmar, France.
Maud SchockService de réanimation médicale,  Hôpital Pasteur de Colmar, Colmar, France.
Olivier AugereauLaboratoire de Microbiologie, Hôpitaux Civils de Colmar, Colmar, France.
Henry LessireService de réanimation médicale,  Hôpital Pasteur de Colmar, Colmar, France.
Charles BouterraService de réanimation médicale,  Hôpital Pasteur de Colmar, Colmar, France.
Lounis BelilitaService de réanimation médicale,  Hôpital Pasteur de Colmar, Colmar, France.
Pierre ReratService de réanimation médicale,  Hôpital Pasteur de Colmar, Colmar, France.
Antonio AlvarezService de réanimation médicale,  Hôpital Pasteur de Colmar, Colmar, France.
Martin MartinotService de maladies infectieuses et tropicales, Hôpital Pasteur de Colmar, Colmar.
Victor GerberService de réanimation médicale,  Hôpital Pasteur de Colmar, Colmar, France.
Hôpital Pasteur · FRHopitaux Civils de Colmar · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Five percent of patients infected with SARS-CoV-2 require advanced respiratory support. The high-flow nasal cannula oxygenotherapy (HFNCO) appears to be effective and safe to reduce the need for mechanical ventilation. However, the factors associated with HFNCO failure as well as the outcomes of patients receiving this noninvasive respiratory strategy remain unclear. Thus, we performed this study to determine factors leading to intubation of SARS-CoV-2 patients treated with HFNCO and patients' outcomes. We retrospectively analyzed the medical charts of patients admitted in our ICU center for acute respiratory failure due to SARS-CoV-2 infection and who initially benefited from HFNCO, between September 1, 2020, and March 1, 2021. We included all adults patients who received HFNCO and compared two groups: those treated with HFNCO alone and those who failed HFNCO. Patients treated with HFNCO and secondarily limited to the use of mechanical ventilation were excluded from the analysis. Sixty-nine patients were included, 33 were treated with HFNCO alone and 36 failed HFNCO. We found more patients with shock in the HFNCO failure group (p = 0.001). The mean IGSII score was higher in the HFNCO failure group (p < 0.001). The minimum PaO

Indexed as

COVID-19Respiratory InsufficiencyAdultCannulaHumansOxygenRespiration, ArtificialRetrospective StudiesSARS-CoV-2OxygenCOVID-19high-flow nasal cannulaintensive care unitmechanical ventilationSARS-CoV-2

Identifiers

PMID34755373
PMCPMC8661912
OpenAlexW3212111742

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.