Evidence map›Paper›PMID 34755215›Full record

ArticleHerz2022

Survey of clinical practice pattern in Germany's certified chest pain units : Adherence to the European Society of Cardiology guidelines on non-ST-segment elevation acute coronary syndrome.

Frank Breuckmann, Stephan Settelmeier, Tienush Rassaf, Felix Post, Winfried Haerer, Johann Bauersachs, Harald Mudra, Thomas Voigtländer, Jochen Senges, Thomas Münzel and 1 more

Open access · hybridAbstract read
In one paragraph

Article in Herz, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

  1. Timing of invasive strategy in patients with non-ST segment elevation acute myocardial infarction: A nationwide retrospective cohort analysis.Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 8 institutions in 1 country.

Frank BreuckmannDepartment of Cardiology and Vascular Medicine, West German Heart and Vascular Center Essen, University Duisburg-Essen, Essen, Germany. frank.breuckmann@uk-essen.de.
Stephan SettelmeierDepartment of Cardiology and Vascular Medicine, West German Heart and Vascular Center Essen, University Duisburg-Essen, Essen, Germany.
Tienush RassafDepartment of Cardiology and Vascular Medicine, West German Heart and Vascular Center Essen, University Duisburg-Essen, Essen, Germany.
Felix PostDepartment of Cardiology, Katholisches Klinikum Koblenz-Montabaur, Koblenz, Germany.
Winfried HaererHeart Clinic Ulm, Ulm, Germany.
Johann BauersachsDepartment of Cardiology and Angiology, Hannover Medical School, Hannover, Germany.
Harald MudraHeart and Vascular Center Munich Maffeistraße and Nymphenburg (Klinikum 3. Orden), Munich, Germany.
Thomas VoigtländerCCB, Cardioangiologisches Centrum Bethanien, Frankfurt am Main, Germany.
Jochen SengesInstitute for Myocardial Infarction Research Foundation, Ludwigshafen, Germany.
Thomas MünzelDepartment of Cardiology, University Medical Center Mainz, Johannes Gutenberg-University Mainz, Mainz, Germany.
Evangelos GiannitsisDepartment of Medicine III, University Hospital Heidelberg, Heidelberg, Germany.
West German Heart and Vascular Center Essen · DECardiovascular Center Bethanien · DEJohannes Gutenberg University Mainz · DEKatholisches Klinikum Koblenz · DEMedizinische Hochschule Hannover · DEMünchen Klinik · DEUniversity and Rehabilitation Clinics Ulm · DEUniversity Hospital Heidelberg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWe aimed to analyze the 2020 standard of care in certified German chest pain units (CPU) with a special focus on non-ST-segment elevation acute coronary syndrome (NSTE-ACS) through a voluntary survey obtained from all certified units, using a prespecified questionnaire.

methodsThe assessment included the collection of information on diagnostic protocols, risk assessment, management and treatment strategies in suspected NSTE-ACS, the timing of invasive therapy in non-ST-segment elevation myocardial infarction (NSTEMI), and the choice of antiplatelet therapy.

resultsThe response rate was 75%. Among all CPUs, 77% are currently using the European Society of Cardiology (ESC) 0/3‑h high-sensitive troponin protocol, and only 20% use the ESC 0/1‑h high-sensitive troponin protocol as a default strategy. Conventional ergometry is still the commonly performed stress test with a utilization rate of 47%. Among NSTEMI patients, coronary angiography is planned within 24 h in 96% of all CPUs, irrespective of the day of the week. Prasugrel is the P2Y12 inhibitor of choice in ST-segment elevation myocardial infarction (STEMI), but despite the impact of the ISAR-REACT 5 trial on selection of antiplatelet therapy, ticagrelor is still favored over prasugrel in NSTE-ACS. If triple therapy is used in NSTE-ACS with atrial fibrillation, it is maintained up to 4 weeks in 51% of these patients.

conclusionThis survey provides evidence that Germany's certified CPUs ensure a high level of guideline adherence and quality of care. The survey also identified areas in need of improvement such as the high utilization rate of stress electrocardiogram (ECG).

Indexed as

Acute Coronary SyndromeCardiologyNon-ST Elevated Myocardial InfarctionST Elevation Myocardial InfarctionChest PainGermanyHumansPlatelet Aggregation InhibitorsPractice Patterns, Physicians'Prasugrel HydrochlorideSurveys and QuestionnairesTroponinPlatelet Aggregation InhibitorsPrasugrel HydrochlorideTroponinAntiplatelet therapyPCIStandard of careTimingTroponin protocol

Identifiers

PMID34755215
PMCPMC8577645
OpenAlexW3213798878

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.