Evidence map›Paper›PMID 34755212›Full record

ArticleApplied microbiology and biotechnology2021

Bacterial degradation of the anti-depressant drug fluoxetine produces trifluoroacetic acid and fluoride ion.

Mohd Faheem Khan, Cormac D Murphy

Abstract read
PubMed Publisher
In one paragraph

Article in Applied microbiology and biotechnology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 39 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Review
  6. Engineering microbiology · 2025
    Article
  7. Review
  8. Fungal mediated production of novel metabolites of meloxicam and their tankyrase-2 inhibition potentials: an in silico study.International microbiology : the official journal of the Spanish Society for Microbiology · 2025
    Article
  9. Article
  10. Article
  11. Article
  12. An Overview of Degradation Strategies for Amitriptyline.International journal of molecular sciences · 2024
    Review
  13. Review
  14. Aryl (β,β',β″-Trifluoro)-Organic letters · 2023
    Article
  15. Article
  16. Changes in tropospheric air quality related to the protection of stratospheric ozone in a changing climate.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2023
    Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Mohd Faheem KhanUCD School of Biomolecular and Biomedical Science, University College Dublin, Belfield, Dublin 4, Ireland.ORCID http://orcid.org/0000-0002-0589-3368
Cormac D MurphyUCD School of Biomolecular and Biomedical Science, University College Dublin, Belfield, Dublin 4, Ireland. cormac.d.murphy@ucd.ie.ORCID http://orcid.org/0000-0002-2137-3338
University College Dublin · IE

Funding

Irish Research Council IRC/GOI-PD/1064
6 · The paper itself

Abstract

Fluoxetine (FLX) is a blockbuster drug with annual sales in the billions of dollars. Its widespread use has resulted in its detection in water courses, where it impacts aquatic life. Investigations on the biodegradation of FLX by microorganisms are important, since augmentation of secondary wastewater treatment by an effective degrader may be one method of improving the drug's removal. In this paper, we demonstrate that common environmental bacteria can use FLX as a sole carbon and energy source. Investigations into the metabolites formed using fluorine-19 nuclear magnetic resonance spectroscopy (

Indexed as

FluoxetinePharmaceutical PreparationsBacteriaBiodegradation, EnvironmentalFluoridesFluorineTrifluoroacetic AcidFluoridesFluorineFluoxetinePharmaceutical PreparationsTrifluoroacetic Acid4-(Trifluoromethyl)phenolBiodegradationFluoride ionFluoxetinePhotodegradationTrifluoroacetate

Identifiers

PMID34755212
OpenAlexW3212838503

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.