Evidence map›Paper›PMID 34755139›Full record

ArticleCell reports. Medicine2021

HIV-1 protection: Antibodies move in for the kill.

Zak A Yaffe, Julie Overbaugh

Open access · goldAbstract readComment
In one paragraph

Article in Cell reports. Medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 54% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Zak A YaffeHuman Biology Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.
Julie OverbaughHuman Biology Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.
Fred Hutch Cancer Center · US

Funding

THE ROLE OF ANTIBODIES IN MOTHER TO CHILD HIV TRANSMISSIONR01AI076105 · NIAID · FRED HUTCHINSON CANCER RESEARCH CENTER · PI OVERBAUGH, JULIE M. · 2008 to 2023
$8.8M
Studying the Contribution of Env-SpecificAntibodies to Mother to Child Transmission of HIV-1F30AI165112 · NIAID · UNIVERSITY OF WASHINGTON · PI YAFFE, ZACHARY A · 2021 to 2023
$141k
NIAID NIH HHS F30 AI165112NIAID NIH HHS R01 AI076105
6 · The paper itself

Abstract

Identifying the immune responses needed for protection against HIV is critical to finding an effective vaccine. In this issue of

Indexed as

HIV-1HIV InfectionsAntibodies, NeutralizingAntibodies, ViralHIV AntibodiesHumansAntibodies, NeutralizingAntibodies, ViralHIV Antibodies

Identifiers

PMID34755139
PMCPMC8561314
OpenAlexW3206941098

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.