Evidence map›Paper›PMID 34755109›Full record

ArticleBrain communications2021

Persistent sodium currents in

Kathleen M Gorman, Colin H Peters, Bryan Lynch, Laura Jones, Dani S Bassett, Mary D King, Peter C Ruben, Richard E Rosch

Open access · goldAbstract read
In one paragraph

Article in Brain communications, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Dravet syndrome: novel insights intoFrontiers in neuroscience · 2025
    Review
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  8. Dependence of cortical neuronal strength-duration properties on TMS pulse shape.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2023
    Article
  9. Review
  10. Review
  11. Review
  12. Article
  13. Review
  14. The L1624Q Variant inFrontiers in pharmacology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 4 countries.

Kathleen M GormanDepartment of Neurology and Clinical Neurophysiology, Children's Health Ireland at Temple Street, Dublin, Ireland.
Colin H PetersDepartment of Biomedical Physiology and Kinesiology, Simon Fraser University, Burnaby, Canada.
Bryan LynchDepartment of Neurology and Clinical Neurophysiology, Children's Health Ireland at Temple Street, Dublin, Ireland.
Laura JonesDepartment of Biomedical Physiology and Kinesiology, Simon Fraser University, Burnaby, Canada.
Dani S BassettDepartments of Bioengineering, Electrical & Systems Engineering, Physics & Astronomy, Neurology, and Psychiatry, University of Pennsylvania, Philadelphia, PA, USA.ORCID https://orcid.org/0000-0002-6183-4493
Mary D KingDepartment of Neurology and Clinical Neurophysiology, Children's Health Ireland at Temple Street, Dublin, Ireland.
Peter C RubenDepartment of Biomedical Physiology and Kinesiology, Simon Fraser University, Burnaby, Canada.
Richard E RoschDepartment of Paediatric Neurology, Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK.ORCID https://orcid.org/0000-0002-0316-5818
Simon Fraser University · CAUniversity College Dublin · IEChildren's Health Ireland at Crumlin · IEKing's College London · GBSanta Fe Institute · US

Funding

Wellcome Trust 209164/Z/17/Z
6 · The paper itself

Abstract

Pathogenic variants in the voltage-gated sodium channel gene (

Indexed as

epileptic encephalopathyHodgkin–Huxley modelnon-inactivating currentSCN1Asodium-channel gating

Identifiers

PMID34755109
PMCPMC8568850
OpenAlexW3201710673

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.