ArticleAnnals of gastroenterological surgery2021
Prognostic significance of osteopenia in patients with colorectal cancer: A retrospective cohort study.
Article in Annals of gastroenterological surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.
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Who cites it
9 citing papers in PubMed, 2 syntheses or guidelines pooled it, 17 citations in OpenAlex.
- Predictive value of osteopenia as prognostic marker for survival and recurrence in patients with gastrointestinal cancers: a systematic review and meta-analysis.Frontiers in medicine · 2025Pooled it
- Prognostic value of preoperative low bone mineral density in patients with digestive cancers: a systematic review and meta-analysis.Archives of osteoporosis · 2022Pooled it
- Imaging-based prognostic factors in patients undergoing thermal ablation for colorectal liver metastases. A retrospective study on the role of sarcopenia parameters and tumor burden score.Radiology and oncology · 2026Article
- Prognostic impact of preoperative osteopenia in elderly patients with lung cancer.World journal of surgical oncology · 2025Article
- Prognostic Impact of Bone Mineral Density Reduction During Neoadjuvant Chemotherapy (NAC) in Patients Undergoing NAC Followed by Esophagectomy for Esophageal Cancer.Annals of gastroenterological surgery · 2025Article
- Impact of osteopenia and neutropenia in patients with colorectal cancer treated with FOLFOXIRI: a retrospective cohort study.International journal of clinical oncology · 2022Article
- Significance of osteopenia in elderly patients undergoing emergency gastrointestinal surgery.Annals of gastroenterological surgery · 2022Article
- Prognostic significance of osteopenia in patients with colorectal cancer: A retrospective cohort study.Annals of gastroenterological surgery · 2021Article
- Preoperative Osteopenia as Risk Factor for Death from Other Diseases After Gastrectomy in Elderly Patients.In vivo (Athens, Greece)Article
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Authors and funding
10 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimWe examined the prognostic impact of osteopenia on the long-term outcomes of patients with colorectal cancer after laparoscopic colectomy along with other nutritional factors, including sarcopenia or the Glasgow Prognostic Score.
methodsThis retrospective cohort study analyzed the data of 230 patients with stage Ⅰ-Ⅲ colorectal cancers who underwent surgical resection between November 2010 and December 2015. Osteopenia and sarcopenia were evaluated by measuring the average pixel density in the mid-vertebral core of the 11th thoracic vertebra on enhanced computed tomography and the psoas muscle mass area at the third lumbar vertebra, respectively. The overall survival and disease-free survival rates were analyzed using Cox proportional hazards model and Kaplan-Meier curves with the log-rank test.
resultsOsteopenia was identified in 43 patients (18.7%). Univariate analysis showed that the disease-free survival rate was significantly worse in patients with stage II-III cancers, vascular invasion, carcinoembryonic antigen (CA) >5.0 ng/mL, CA19-9 > 37.0 U/mL, sarcopenia, and osteopenia (all
conclusionPreoperative osteopenia could be a strong predictor of long-term outcomes in patients undergoing resection for colorectal cancer.
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