Evidence map›Paper›PMID 34754987›Full record

ArticleJACC. Basic to translational science

Human Atherosclerotic Plaque Progression Is Dependent on Apoptosis According to Bomb-Pulse

Andreas Edsfeldt, Kristina Eriksson Stenström, Jiangming Sun, Nuno Dias, Göran Skog, Pratibha Singh, Sören Mattsson, Jan Nilsson, Isabel Gonçalves

Open access · goldAbstract read
In one paragraph

Article in JACC. Basic to translational science. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Sjogren's Disease and Elevated Cardiovascular Risk: Mechanisms and Treatment.Journal of cardiovascular development and disease · 2025
    Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Andreas EdsfeldtDepartment of Clinical Sciences Malmö, Lund University, Malmö, Sweden.
Kristina Eriksson StenströmDepartment of Physics, Lund University, Lund, Sweden.
Jiangming SunDepartment of Clinical Sciences Malmö, Lund University, Malmö, Sweden.
Nuno DiasDepartment of Clinical Sciences Malmö, Lund University, Malmö, Sweden.
Göran SkogDepartment of Geology, Quaternary Sciences, Lund University, Lund, Sweden.
Pratibha SinghDepartment of Clinical Sciences Malmö, Lund University, Malmö, Sweden.
Sören MattssonDepartment of Translational Medicine, Medical Radiation Physics Malmö, Lund University, Malmö, Sweden.
Jan NilssonDepartment of Clinical Sciences Malmö, Lund University, Malmö, Sweden.
Isabel GonçalvesDepartment of Clinical Sciences Malmö, Lund University, Malmö, Sweden.
Lund University · SEMalmö University · SESkåne University Hospital · SEWallenberg Wood Science Center · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Individuals with rapidly progressing atherosclerotic plaques are at higher risk of experiencing acute complications. Currently, we lack knowledge regarding factors in human plaque that cause rapid progression. Using the

Indexed as

14C bomb pulseAMS, accelerator mass spectrometryapoptosisatherosclerosisIQR, interquartile rangePCNA, proliferating-cell nuclear antigenplaque progressionSMC, smooth muscle cellTUNEL, terminal deoxynucleotidyl transferase deoxyuridine triphosphate nick-end labeling

Identifiers

PMID34754987
PMCPMC8559321
OpenAlexW3210151940

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.