Evidence map›Paper›PMID 34754954›Full record

ArticlePhysics and imaging in radiation oncology2021

Quality assurance of dysphagia-optimised intensity modulated radiotherapy treatment planning for head and neck cancer.

Justine Tyler, David Bernstein, Matthew Seithel, Keith Rooney, Imran Petkar, Elizabeth Miles, Catharine H Clark, Emma Hall, Chris Nutting

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Physics and imaging in radiation oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Impact of on-trial IGRT quality assurance in an international adaptive radiotherapy trial for participants with bladder cancer.Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology · 2024
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Justine TylerNational Radiotherapy Trials Quality Assurance Group, The Royal Marsden NHS Foundation Trust, 203 Fulham Road, London SW3 6JJ, UK.
David BernsteinNational Radiotherapy Trials Quality Assurance Group, The Royal Marsden NHS Foundation Trust, 203 Fulham Road, London SW3 6JJ, UK.
Matthew SeithelNational Radiotherapy Trials Quality Assurance Group, The Royal Marsden NHS Foundation Trust, 203 Fulham Road, London SW3 6JJ, UK.
Keith RooneyRadiotherapy Department, The Royal Marsden NHS Foundation Trust, 203 Fulham Road, London SW3 6JJ, UK.
Imran PetkarThe Institute of Cancer Research, 123 Old Brompton Road, London SW7 3RP, UK.
Elizabeth MilesNational Radiotherapy Trials Quality Assurance Group, Mount Vernon Cancer Centre, Northwood, Middlesex HA6 2RN, UK.
Catharine H ClarkNational Radiotherapy Trials Quality Assurance Group, Mount Vernon Cancer Centre, Northwood, Middlesex HA6 2RN, UK.
Emma HallThe Institute of Cancer Research, 123 Old Brompton Road, London SW7 3RP, UK.
Chris NuttingThe Institute of Cancer Research, 123 Old Brompton Road, London SW7 3RP, UK.

Funding

Cancer Research UK 17425
6 · The paper itself

Abstract

This study aimed to assess the impact of the margin applied to the clinical target volume, to create the planning target volume, on plan quality of a novel dysphagia-optimised intensity modulated radiotherapy technique developed within a head and neck cancer multicentre randomised controlled trial. Protocol compliant plans were used for a single benchmark planning case. Larger margins were associated with higher doses to adjacent organs at risk, particularly the inferior pharyngeal constrictor muscle, but coincided with some improved low dose target coverage. A 3 mm margin is recommended for this technique if local practices allow.

Indexed as

CERR, Computational Environment for Radiotherapy ResearchDARS, dysphagia/aspiration related structuresDICOM, Digital Imaging and Communications in MedicineDO-IMRT, dysphagia optimised intensity modulated radiotherapyDysphagiaHead and neck cancerICR-CTSU, Clinical Trials and Statistics Unit and the Institute of Cancer ResearchIntensity modulated radiotherapy (IMRT)IPCM, inferior pharyngeal constrictor muscleNIHR, National Institute for Health ResearchPAF, plan assessment formQuality assuranceRandomised controlled trialRTQA, radiotherapy quality assuranceRTTQA, UK’s National Radiotherapy Trials Quality Assurance GroupS-IMRT, standard intensity modulated radiotherapySMPCM, superior and middle pharyngeal constrictor musclesTMG, Trial Management GroupVolumetric arc therapy (VMAT)

Identifiers

PMID34754954
PMCPMC8560997

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.