Evidence map›Paper›PMID 34754871›Full record

ArticleWorld journal of clinical cases2021

Itraconazole therapy for infant hemangioma: Two case reports.

Zhe Liu, Sha Lv, Shuang Wang, Sheng-Ming Qu, Gui-Yun Zhang, Yi-Tong Lin, Lei Yang, Fu-Qiu Li

Open access · diamondAbstract readCase Reports
In one paragraph

Article in World journal of clinical cases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Zhe LiuDepartment of Dermatology, The Second Hospital of Jilin University, Changchun 130041, Jilin Province, China.
Sha LvDepartment of Dermatology, The Second Hospital of Jilin University, Changchun 130041, Jilin Province, China.
Shuang WangDepartment of Dermatology, The Second Hospital of Jilin University, Changchun 130041, Jilin Province, China.
Sheng-Ming QuDepartment of Dermatology, The Second Hospital of Jilin University, Changchun 130041, Jilin Province, China.
Gui-Yun ZhangDepartment of Dermatology, The Second Hospital of Jilin University, Changchun 130041, Jilin Province, China.
Yi-Tong LinDepartment of Dermatology, The Second Hospital of Jilin University, Changchun 130041, Jilin Province, China.
Lei YangDepartment of Dermatology, The Second Hospital of Jilin University, Changchun 130041, Jilin Province, China.
Fu-Qiu LiDepartment of Dermatology, The Second Hospital of Jilin University, Changchun 130041, Jilin Province, China. lifuqiu1234@126.com.
Second Affiliated Hospital of Jilin University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundInfantile hemangiomas (IHs) are the most common childhood benign tumors, showing distinctive progression characteristics and outcomes. Due to the high demand for aesthetics among parents of IH babies, early intervention is critical in some cases. β-Adrenergic blockers and corticosteroids are first-line medications for IHs, while itraconazole, an antifungal medicine, has shown positive results in recent years. CASE SUMMARY: In the present study, itraconazole was applied to treat two IH cases. The therapeutic course lasted 80-90 d, during which the visible lesion faded by more than 90%. Moreover, no obvious side effects were reported, and the compliance of the baby and parents was desirable.

conclusionAlthough these outcomes further support itraconazole as an effective therapeutic choice for IHs, large-scale clinical and basic studies are still warranted to improve further treatment.

Indexed as

Case reportHemangiomasInfantItraconazoleOralTherapeutics

Identifiers

PMID34754871
PMCPMC8554448
OpenAlexW3204273703

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.