Evidence map›Paper›PMID 34754848›Full record

ArticleWorld journal of clinical cases2021

Validated tool for early prediction of intensive care unit admission in COVID-19 patients.

Hao-Fan Huang, Yong Liu, Jin-Xiu Li, Hui Dong, Shan Gao, Zheng-Yang Huang, Shou-Zhi Fu, Lu-Yu Yang, Hui-Zhi Lu, Liao-You Xia and 3 more

Abstract read
In one paragraph

Article in World journal of clinical cases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Prediction models for COVID-19 disease outcomes.Emerging microbes & infections · 2024
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Hao-Fan HuangSchool of Biomedical Engineering, Health Science Center, Shenzhen University, Shenzhen 518060, Guangdong Province, China.
Yong LiuExpert Panel of Shenzhen 2019-nCoV Pneumonia, Shenzhen Hospital, Southern Medical University, Shenzhen 518000, Guangdong Province, China.
Jin-Xiu LiDepartment of Critical Care Medicine, Shenzhen Third People's Hospital, Second Hospital Affiliated to Southern University of Science and Technology, Shenzhen 518112, Guangdong Province, China.
Hui DongDepartment of ICU/Emergency, Wuhan Third Hospital, Wuhan University, Wuhan 430000, Hubei Province, China.
Shan GaoSchool of Biomedical Engineering, Health Science Center, Shenzhen University, Shenzhen 518060, Guangdong Province, China.
Zheng-Yang HuangSchool of Biomedical Engineering, Health Science Center, Shenzhen University, Shenzhen 518060, Guangdong Province, China.
Shou-Zhi FuDepartment of ICU/Emergency, Wuhan Third Hospital, Wuhan University, Wuhan 430000, Hubei Province, China.
Lu-Yu YangDepartment of ICU/Emergency, Wuhan Third Hospital, Wuhan University, Wuhan 430000, Hubei Province, China.
Hui-Zhi LuDepartment of ICU/Emergency, Wuhan Third Hospital, Wuhan University, Wuhan 430000, Hubei Province, China.
Liao-You XiaDepartment of ICU/Emergency, Wuhan Third Hospital, Wuhan University, Wuhan 430000, Hubei Province, China.
Song CaoDepartment of ICU/Emergency, Wuhan Third Hospital, Wuhan University, Wuhan 430000, Hubei Province, China.
Yi GaoSchool of Biomedical Engineering, Health Science Center, Shenzhen University, Shenzhen 518060, Guangdong Province, China.
Xia-Xia YuSchool of Biomedical Engineering, Health Science Center, Shenzhen University, Shenzhen 518060, Guangdong Province, China. xiaxiayu@szu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe novel coronavirus disease 2019 (COVID-19) pandemic is a global threat caused by the severe acute respiratory syndrome coronavirus-2.

aimTo develop and validate a risk stratification tool for the early prediction of intensive care unit (ICU) admission among COVID-19 patients at hospital admission.

methodsThe training cohort included COVID-19 patients admitted to the Wuhan Third Hospital. We selected 13 of 65 baseline laboratory results to assess ICU admission risk, which were used to develop a risk prediction model with the random forest (RF) algorithm. A nomogram for the logistic regression model was built based on six selected variables. The predicted models were carefully calibrated, and the predictive performance was evaluated and compared with two previously published models.

resultsThere were 681 and 296 patients in the training and validation cohorts, respectively. The patients in the training cohort were older than those in the validation cohort (median age: 63.0

conclusionOur model can identify ICU admission risk in COVID-19 patients at admission, who can then receive prompt care, thus improving medical resource allocation.

Indexed as

COVID-19Intensive care unitsMachine learningPrognostic predictive modelRisk stratification

Identifiers

PMID34754848
PMCPMC8554435

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.