Evidence map›Paper›PMID 34754825›Full record

ArticleMethodsX2021

Assay of ethanol and congener alcohols in serum and beverages by headspace gas chromatography/mass spectrometry.

Cora Wunder, Werner Pogoda, Alexander Paulke, Stefan W Toennes

Open access · goldAbstract read
In one paragraph

Article in MethodsX, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.1field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Cora WunderDepartment of Forensic Toxicology, University Hospital, Goethe University, Institute of Legal Medicine, Frankfurt/Main, Germany.
Werner PogodaDepartment of Forensic Toxicology, University Hospital, Goethe University, Institute of Legal Medicine, Frankfurt/Main, Germany.
Alexander PaulkeDepartment of Forensic Toxicology, University Hospital, Goethe University, Institute of Legal Medicine, Frankfurt/Main, Germany.
Stefan W ToennesDepartment of Forensic Toxicology, University Hospital, Goethe University, Institute of Legal Medicine, Frankfurt/Main, Germany.
Goethe University Frankfurt · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The analysis of ethanol and of its congeners in blood plays an important role in forensic cases, especially when allegations are made that alcohol has been consumed after an accident. In alcoholic beverages, congener alcohols are by-products and are generated during fermentation. The assay of these compounds in serum samples and beverages has been previously performed using headspace-gas chromatography-flame ionization detection methods (HS-GC-FID). As an alternative, a robust headspace-gas chromatography-mass spectrometry (HS-GC-MS) procedure was developed and validated, which has the following advantages:•Simultaneous determination of ethanol, congener alcohols and other endogenous substances.•Reduction of matrix interference by increasing selectivity and specificity.•Clear separation of the positional isomers 3-methyl-1-butanol and 2-methyl-1-butanol.

Indexed as

1-propanolAlcoholCal, calibratorCV, coefficients of variationEI, electron impact ionizationFID, flame ionization detectionGC, gas chromatographyGTFCh, Gesellschaft für Toxikologische und Forensische ChemieHS, headspaceISTD, internal standardLLOQ, lower limit of quantitationLOD, limit of detectionMethanolMethod validationMS, mass spectrometryPost-offence drinkingQC, quality control

Identifiers

PMID34754825
PMCPMC8563810
OpenAlexW3209749495

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.