Evidence map›Paper›PMID 34754700›Full record

ReviewCureus2021

Middle Meningeal Artery Embolization and the Treatment of a Chronic Subdural Hematoma.

Likowsky L Désir, Randy D'Amico, Thomas Link, Danilo Silva, Jason A Ellis, Omer Doron, David J Langer, Rafael Ortiz, Yafell Serulle

Registry-linked trialOpen access · diamondAbstract readReview
In one paragraph

Review in Cureus, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06466733 (Puerto Rico Embolization of the Middle Meningeal Artery for the Treatment of Chronic Subdural Hematoma Trial), which is not on this map. Cited by 25 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 2 pooled it
2.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06466733 nanot yet recruitingnot on this mapstarted 2025, after this paper: background citation

Puerto Rico Embolization of the Middle Meningeal Artery for the Treatment of Chronic Subdural Hematoma Trial (PREMMA)

TypeinterventionalSponsorJuan M. Ramos AcevedoRan2025 to 2032Enrolled658ConditionsChronic Subdural HematomaArmsEmbolization of the middle meningeal artery, Surgical Evacuation via burr hole or craniotomy
3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 2 syntheses or guidelines pooled it, 40 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Coil embolization alone appears sufficient for middle meningeal artery embolization.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2026
    Article
  5. Observational
  6. Article
  7. Preoperative middle meningeal artery embolization is associated with reduced reoperation rates in chronic subdural hematoma.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2025
    Article
  8. Article
  9. Article
  10. Middle meningeal artery embolization for migraine: A review.Surgical neurology international · 2025
    Review
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Likowsky L DésirDepartment of Neurological Surgery, Lenox Hill Hospital, New York City, USA.
Randy D'AmicoDepartment of Neurological Surgery, Lenox Hill Hospital, New York City, USA.
Thomas LinkDepartment of Neurological Surgery, Lenox Hill Hospital, New York City, USA.
Danilo SilvaDepartment of Neurological Surgery, Lenox Hill Hospital, New York City, USA.
Jason A EllisDepartment of Neurological Surgery, Lenox Hill Hospital, New York City, USA.
Omer DoronDepartment of Neurological Surgery, Lenox Hill Hospital, New York City, USA.
David J LangerDepartment of Neurological Surgery, Lenox Hill Hospital, New York City, USA.
Rafael OrtizDepartment of Neurological Surgery, Lenox Hill Hospital, New York City, USA.
Yafell SerulleDepartment of Neurological Surgery, Lenox Hill Hospital, New York City, USA.
Neurological Surgery · USLenox Hill Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic subdural hematoma (cSDH) is a common pathology that typically affects the elderly. It is believed to occur due to injury to the dural border cells, which creates an inflammation/proliferation reaction. Ineffective repair leads to the formation of a new external layer of cells and fragile capillaries, which damage easily and can worsen the condition. Conventionally, asymptomatic cSDH is managed by observation, and symptomatic cases are treated by surgical evacuation. Unfortunately, recurrence rates of the SDH following surgical evacuation can be high. One treatment option for SDH involves embolization of the middle meningeal artery (MMA). The MMA provides blood supply to the dura mater and feeds the membrane capillaries covering the SDH. MMA embolization blocks the blood flow to this system and can promote hematoma resolution. In this paper, we review the existing literature on MMA embolization and discuss the underlying pathophysiology of cSDH.

Indexed as

chronic subdural hematoma (csdh)middle meningeal artery embolizationmiddle meningeal artery (mma)prophylaxissubdural hematoma (sdh)

Identifiers

PMID34754700
PMCPMC8570051
OpenAlexW3206643549

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.