Evidence map›Paper›PMID 34754507›Full record

ArticleGlobal challenges (Hoboken, NJ)2021

On-Site, On-Demand 3D-Printed Nasopharyngeal Swabs to Improve the Access of Coronavirus Disease-19 Testing.

Jiaxi Song, Jeremy Korunes-Miller, Rohin Banerji, Yuanqiao Wu, Shoreh Fazeli, Hanqiao Zheng, Beverley Orr, Elise Morgan, Christopher Andry, Joel Henderson and 3 more

Open access · goldAbstract read
In one paragraph

Article in Global challenges (Hoboken, NJ), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Jiaxi SongDepartment of Biomedical Engineering Boston University Boston Medical Center Boston MA 02215 USA.
Jeremy Korunes-MillerDepartment of Biomedical Engineering Boston University Boston Medical Center Boston MA 02215 USA.
Rohin BanerjiDepartment of Biomedical Engineering Boston University Boston Medical Center Boston MA 02215 USA.
Yuanqiao WuDepartment of Mechanical Engineering Boston University Boston Medical Center Boston MA 02215 USA.
Shoreh FazeliDepartment of Pathology & Laboratory Medicine Boston University Boston Medical Center Boston MA 02215 USA.
Hanqiao ZhengDepartment of Pathology & Laboratory Medicine Boston University Boston Medical Center Boston MA 02215 USA.
Beverley OrrClinical Microbiology & Molecular Diagnostics Boston University Boston Medical Center Boston MA 02215 USA.
Elise MorganDepartment of Biomedical Engineering Boston University Boston Medical Center Boston MA 02215 USA.
Christopher AndryDepartment of Pathology & Laboratory Medicine Boston University Boston Medical Center Boston MA 02215 USA.
Joel HendersonDepartment of Pathology & Laboratory Medicine Boston University Boston Medical Center Boston MA 02215 USA.
Nancy S MillerDepartment of Pathology & Laboratory Medicine Boston University Boston Medical Center Boston MA 02215 USA.
Alice WhiteDepartment of Biomedical Engineering Boston University Boston Medical Center Boston MA 02215 USA.
Mark W GrinstaffDepartment of Biomedical Engineering Boston University Boston Medical Center Boston MA 02215 USA.ORCID https://orcid.org/0000-0002-5453-3668
Boston University · US

Funding

Project-005UL1TR001430 · NCATS · BOSTON UNIVERSITY MEDICAL CAMPUS · PI BAIR-MERRITT, MEGAN H, CENTER, DAVID M. · 2015 to 2024
$52.3M
NCATS NIH HHS UL1 TR001430
6 · The paper itself

Abstract

Diagnostic testing that facilitates containment, surveillance, and treatment of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), or future respiratory viruses, depends on a sample collection device that efficiently collects nasopharyngeal tissue and that can be manufactured on site when an outbreak or public health emergency is declared by a government. Here two novel stereolithography-based three-dimensional (3D)-printed nasopharyngeal swabs are reported which are made using a biocompatible and sterilizable photoresist. Such swabs are readily manufactured on-site and on-demand to ensure availability, if supply chain shortages emerge. Additionally, the 3D-printed swabs easily adapt to current workflow and testing procedures in hospital clinical laboratories to allow for effortless scaling up of test kits. Finally, the 3D-printed nasopharyngeal swabs demonstrate concordant SARS-CoV-2 testing results between the 3D-printed swabs and the COPAN commercial swabs, and enable detection of SARS-CoV-2 in clinical samples obtained from autopsies.

Indexed as

3D printingcoronavirus disease‐19nasopharyngeal swabSARS‐CoV‐2

Identifiers

PMID34754507
PMCPMC8562062
OpenAlexW3195456314

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.