ArticleClinical kidney journal2021
The association of glucose metabolism and kidney function in middle-aged adults.
Article in Clinical kidney journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
8 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.
- Association between prediabetes and nephropathy: a comprehensive systematic review and meta-analysis.BMC nephrology · 2026Pooled it
- Association between estimated glucose disposal rate and kidney function decline in different glucose tolerance statuses from the 4 C study.Acta diabetologica · 2025Article
- Protective Effects of a ProbioticFoods (Basel, Switzerland) · 2025Article
- Associations of physiologic subtypes based on HOMA2 indices of β-cell function and insulin sensitivity with the risk of kidney function decline, cardiovascular disease, and all-cause mortality from the 4C study.Cardiovascular diabetology · 2024Article
- Cardiometabolic traits mediating the effect of education on the risk of DKD and CKD: a Mendelian randomization study.Frontiers in nutrition · 2024Article
- Glycemia is associated with subclinical atherosclerosis through renal function in nondiabetic apparently healthy adults: a mediation analysis.Hypertension research : official journal of the Japanese Society of Hypertension · 2023Article
- Microvascular and Endothelial Dysfunction in Prediabetes.Life (Basel, Switzerland) · 2023Review
- Analysis of retinal and choroidal characteristics in patients with early diabetic retinopathy using WSS-OCTA.Frontiers in endocrinology · 2023Article
Corrections and comments
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPrevious clinical studies have shown that various measures of glucose metabolism are associated with a risk of chronic kidney disease in different populations, but results were not consistent. In this study we assessed measures of glucose metabolism and their association with kidney function in a population-based study.
methodsThe Netherlands Epidemiology of Obesity study is a population-based cohort study of middle-aged men and women. We categorized the study population according to glycaemic levels into normoglycaemia (reference group), pre-diabetes mellitus (pre-DM), known DM and newly diagnosed DM. Outcome variables were serum creatinine, estimated glomerular filtration rate (eGFR), glomerular hyperfiltration (defined as an eGFR >90th percentile; >102 mL/min/1.73 m
resultsOf the total population (
conclusionsBoth fasting and post-prandial glucose and HOMA-B, but not measures of insulin resistance, were associated with glomerular hyperfiltration, while fasting glucose was also associated with microalbuminuria.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.