Evidence map›Paper›PMID 34754401›Full record

ArticleWorld journal of cardiology2021

Elderly patients with non-cardiac admissions and elevated high-sensitivity troponin: the prognostic value of renal function.

Ioanna Samara, Stavroula Tsiara, Michail I Papafaklis, Konstantinos Pappas, Georgios Kolios, Nikolaos Vryzas, Lampros K Michalis, Eleni T Bairaktari, Christos S Katsouras

Open access · diamondAbstract read
In one paragraph

Article in World journal of cardiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Ioanna SamaraSecond Department of Cardiology, University Hospital of Ioannina, Ioannina 45110, Greece.
Stavroula TsiaraSecond Department of Internal Medicine, University Hospital of Ioannina, Ioannina 45110, Greece.
Michail I PapafaklisSecond Department of Cardiology, University Hospital of Ioannina, Ioannina 45110, Greece.
Konstantinos PappasSecond Department of Cardiology, University Hospital of Ioannina, Ioannina 45110, Greece.
Georgios KoliosLaboratory of Biochemistry, University Hospital of Ioannina, Ioannina 45110, Greece.
Nikolaos VryzasSecond Department of Cardiology, University Hospital of Ioannina, Ioannina 45110, Greece.
Lampros K MichalisSecond Department of Cardiology, University Hospital of Ioannina, Ioannina 45110, Greece.
Eleni T BairaktariLaboratory of Clinical Chemistry, School of Health Sciences, Faculty of Medicine, University of Ioannina, Ioannina 45110, Greece.
Christos S KatsourasSecond Department of Cardiology, University Hospital of Ioannina, Ioannina 45110, Greece. cskats@yahoo.com.
University Hospital of Ioannina · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHigh-sensitivity cardiac troponin (hs-cTn) levels are frequently elevated in elderly patients presenting to the emergency department for non-cardiac events. However, most studies on the role of elevated hs-cTn in elderly populations have investigated the prognostic value of hs-cTn in patients with a specific diagnosis or have assessed the relationship between hs-cTn and comorbidities.

aimTo investigate the in-hospital prognosis of consecutive elderly patients admitted to the Internal Medicine Department with acute non-cardiac events and increased hs-cTnI levels.

methodsIn this retrospective study, we selected patients who were aged ≥ 65 years and admitted to the Internal Medicine Department of our hospital between January 2019 and December 2019 for non-cardiac reasons. Eligible patients were those who had hs-cTnI concentrations ≥ 100 ng/L. We investigated the independent predictors of in-hospital mortality by multivariable logistic regression analysis.

resultsOne hundred and forty-six patients (59% female) were selected with an age range from 65 to 100 (mean ± SD: 85.4 ± 7.61) years. The median hs-cTnI value was 284.2 ng/L. For 72 (49%) patients the diagnosis of hospitalization was an infectious disease. The overall in-hospital mortality was 32% (47 patients). Individuals who died did not have higher hs-cTnI levels compared with those who were discharged alive (median: 314.8

conclusionMyocardial injury is a malignant condition in elderly patients admitted to the hospital for non-cardiac reasons. The presence of severe renal impairment is a marker of extremely high in-hospital mortality.

Indexed as

ElderlyHigh sensitivity troponinInternal medicineNon-cardiac admissionsPrognosisRenal function

Identifiers

PMID34754401
PMCPMC8554362
OpenAlexW3209442053

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.