Evidence map›Paper›PMID 34754275›Full record

ArticleMediators of inflammation2021

Association of Inflammatory Markers/Cytokines with Cardiovascular Risk Manifestation in Patients with Endometriosis.

Uzma Rafi, Shaaf Ahmad, Syeda Shazia Bokhari, Muhammad Amir Iqbal, Amna Zia, Muhammad Amjad Khan, Nabila Roohi

Open access · goldAbstract read
In one paragraph

Article in Mediators of inflammation, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

  1. Association Between TNF-Alpha Levels and Atrial Fibrillation Outcomes: A Systematic Review and Meta-Analysis.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
    Pooled it
  2. Bioactive factors in endometriosis peritoneal fluid remodel human cardiomyocytes.American journal of physiology. Heart and circulatory physiology · 2026
    Article
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  20. IL-17: an important pathogenic factor in endometriosis.International journal of medical sciences · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Uzma RafiInstitute of Zoology, Physiology/Endocrinology Laboratory, University of the Punjab, Lahore, Pakistan.ORCID https://orcid.org/0000-0002-1063-1880
Shaaf AhmadKing Edward Medical University, 54000 Lahore, Pakistan.ORCID https://orcid.org/0000-0003-0749-187X
Syeda Shazia BokhariInstitute of Zoology, Physiology/Endocrinology Laboratory, University of the Punjab, Lahore, Pakistan.ORCID https://orcid.org/0000-0001-7545-8823
Muhammad Amir IqbalInstitute of Zoology, Physiology/Endocrinology Laboratory, University of the Punjab, Lahore, Pakistan.ORCID https://orcid.org/0000-0002-5097-2065
Amna ZiaLady Willingdon Hospital, Lahore, Pakistan.
Muhammad Amjad KhanDepartment of Biology, Lahore Garrison University, Pakistan.ORCID https://orcid.org/0000-0002-0071-6979
Nabila RoohiInstitute of Zoology, Physiology/Endocrinology Laboratory, University of the Punjab, Lahore, Pakistan.ORCID https://orcid.org/0000-0002-2396-5433
University of the Punjab · PKKing Edward Medical University · PKLahore Garrison University · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study is aimed at determining the association of inflammatory markers and proinflammatory cytokines with cardiovascular risk manifestation in women with endometriosis as compared to healthy controls. A total of 181 females of reproductive age with the absence of other inflammatory or autoimmune disorders and a lack of hormonal therapy for at least 6 months voluntarily participated in this investigation. Patients were 81 females, laparoscopically diagnosed with endometriosis, while the control group comprised 80 healthy females without any pelvic pathology. All subjects were 20-40 years of age. Exclusion criteria were diabetes, obesity, hypertension, metabolic diseases, cardiovascular, and renal disorders. C-reactive protein, fibrinogen, homocysteine, interleukin-17, and interleukin-33 were analyzed using commercially available ELISA kits. For statistical interpretation, the unpaired Student "

Indexed as

Cardiovascular DiseasesEndometriosisCytokinesFemaleHeart Disease Risk FactorsHumansInflammationRisk FactorsCytokines

Identifiers

PMID34754275
PMCPMC8572614
OpenAlexW3208437857

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.