Evidence map›Paper›PMID 34754237›Full record

ArticleCancer management and research2021

Survival Effects of Radiotherapy on Patients Newly Diagnosed with Distant Metastatic Nasopharyngeal Carcinoma in Non-High-Incidence Areas.

Yongqiang Yang, Xiaole Li, Pengcheng Zhou, Xiaoyu Deng, Yingyi Wang, Qianqian Dang, Yingjuan Zheng, Daoke Yang

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Article in Cancer management and research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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2citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Yongqiang YangDepartment of Radiotherapy, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, People's Republic of China.
Xiaole LiDepartment of Radiotherapy, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, People's Republic of China.
Pengcheng ZhouDepartment of Radiotherapy, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, People's Republic of China.
Xiaoyu DengDepartment of Radiotherapy, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, People's Republic of China.
Yingyi WangDepartment of Radiotherapy, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, People's Republic of China.
Qianqian DangDepartment of Radiotherapy, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, People's Republic of China.
Yingjuan ZhengDepartment of Radiotherapy, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, People's Republic of China.
Daoke YangDepartment of Radiotherapy, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo analyze the effects of radiotherapy and its timing on the survival and safety of patients with newly diagnosed distant metastatic NPC in non-high-incidence areas. PATIENTS AND

methodsWe retrospectively analyzed 94 newly diagnosed NPC patients with distant metastatic admitted to our hospital from January 2011 to June 2018. They were divided into three groups: no radiotherapy group received chemotherapy alone, early radiotherapy group was combined with radiotherapy during 1 to 3 cycles of chemotherapy, and late radiotherapy group was combined with radiotherapy after 4-6 cycles of chemotherapy were effective. The efficacy and side effects of the three groups were compared, and the prognostic factors were analyzed.

resultsThe 6-month, 1-year and 2-year PFS were 53.6%, 14.3% and 3.6% in no radiotherapy group, 71.0%, 38.7% and 19.4% in early radiotherapy group, 88.6%, 48.6% and 22.9% in late radiotherapy group; the radiotherapy groups were better than the no radiotherapy group, and the difference was statistically significant (

conclusionEarly and late combined radiotherapy had similar clinical efficacy and both prolonged PFS and OS for patients with newly diagnosed distant metastatic NPC in non-high-risk areas. If chemotherapy response is expected to be poor, radiotherapy can be received early.

Indexed as

metastasisnasopharyngeal carcinomanon-high-incidence areaprognosisradiotherapy

Identifiers

PMID34754237
PMCPMC8572028

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.