ArticleScientific reports2021
Prevalence of oropharyngeal dysphagia in geriatric patients and real-life associations with diseases and drugs.
Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 2 of them syntheses that pooled it.
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Who cites it
31 citing papers in PubMed, 2 syntheses or guidelines pooled it, 65 citations in OpenAlex.
- Prevalence and influencing factors of oral frailty in older adults with diabetes: a systematic review and meta-analysis.Frontiers in public health · 2025Pooled it
- The global prevalence of oropharyngeal dysphagia in different populations: a systematic review and meta-analysis.Journal of translational medicine · 2022Pooled it
- Valbenazine Sprinkle: An Alternative Formulation of Valbenazine for Oral Administration in Patients With Dysphagia.Clinical and translational science · 2025Trial
- Opioids to Treat Chronic Pain in the Older Adult: A Clinical Consensus to Guarantee Safety and Avoid Adverse Events.Drugs & aging · 2026Review
- Article
- The Aging Esophagus: Contraction Reserve on High-Resolution Manometry Declines With Age.Neurogastroenterology and motility · 2026Article
- Therapeutic strategies for Huntington's disease: current approaches and future direction.Neurodegenerative disease management · 2026Review
- Effects of Thickening Agents Used in Dysphagia on the In Vitro Dissolution of Gliclazide.Pharmacy (Basel, Switzerland) · 2026Article
- Article
- Article
- Associations of malnutrition factors with dysphagia mediated by ADL among nursing home residents.Wiener klinische Wochenschrift · 2025Article
- Association between oral dryness and dysphagia in community-dwelling older population.The journal of nutrition, health & aging · 2025Article
- Risk Factors for Oropharyngeal Dysphagia in Older Adults - Evidence from Consorci Sanitari Del Maresme and Mataró University Hospital, Catalonia, Spain.Aging and disease · 2025Article
- The profile of gastrointestinal dysfunction in prodromal to late-stage Parkinson's disease.NPJ Parkinson's disease · 2025Article
- Self-perception and clinical presentation of eating and swallowing difficulties within elderly care.The South African journal of communication disorders = Die Suid-Afrikaanse tydskrif vir Kommunikasieafwykings · 2025Article
- Clinical Pharmacist's Role in Preventing and Managing Drug-Induced Oral Ulceration: A Bisphosphonate Case in an Older Adult Care Setting.Case reports in dentistry · 2025Article
- The impact of polypharmacy and oral nutritional supplementation on nutritional status in patients residing in a long-term care facility.Frontiers in nutrition · 2025Article
- Individual Pharmacotherapy Management (IPM-II) for Patient and Drug Safety in Polypharmacy via Clinical Electronic Health Record Is Associated with Significant Fall Prevention.Pharmaceuticals (Basel, Switzerland) · 2024Article
- A Drug Safety Briefing (II) in Transplantation from Real-World Individual Pharmacotherapy Management to Prevent Patient and Graft from Polypharmacy Risks at the Very Earliest Stage.Pharmaceuticals (Basel, Switzerland) · 2024Review
- Oral Health-Related Factors Associated with Dysphagia Risk among Older, Healthy, Community-Dwelling Korean Adults: A Pilot Study.Healthcare (Basel, Switzerland) · 2024Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Risk factors for oropharyngeal dysphagia (OD) in elderly patients are mainly central nervous system (CNS) and structural organic diseases or presbyphagia. We analysed the OD prevalence and association of OD with multimorbidity and polypharmacy using real-life data to complete this spectrum, with a focus on further and iatrogenic risk. This was a cross-sectional retrospective study based on a random sample of 200 patients admitted to a geriatric hospital. Data analysis included diagnoses, the detailed list of drugs, and an intense clinical investigation of swallowing according to Stanschus to screen for OD in each patient. The mean patient age was 84 ± 6.5 years. The prevalence of OD was 29.0%, without an effect of age, but a higher rate was found in men and in nursing home residents and an elevated risk of pneumonia. OD risk was slight in diabetes mellitus and COPD, and pronounced in CNS diseases. A relevant OD association was found, even after adjusting for CNS diseases, with antipsychotics, benzodiazepines, anti-Parkinson drugs, antidepressants, and antiepileptics. Further risk of OD was found with beta-blockers, alpha-blockers, opioids, antiemetics, antivertiginosa or antihistamines, metoclopramide, domperidone, anticholinergics, loop diuretics, urologics, and ophthalmics. From real-life data in patients with and without CNS diseases, we identified drug groups associated with a risk of aggravating/inducing OD. Restrictive indications for these drugs may be a preventative contribution, requiring implementation in dysphagia guidelines and an integrative dysphagia risk scale that considers all associated and cumulative medication risks in addition to diseases.
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