ArticleScientific reports2021
Three-dimensional semi-automated volumetric assessment of the pulp space of teeth following regenerative dental procedures.
Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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13 citing papers in PubMed, 38 citations in OpenAlex.
- Computational Insights into Root Canal Treatment: A Survey of Selected Methods in Imaging, Segmentation, Morphological Analysis, and Clinical Management.Dentistry journal · 2025Review
- Assessment of volumetric changes after regenerative endodontic procedures using semiautomated and 3D U-NET automated CBCT segmentation: a retrospective cohort study.BMC oral health · 2025Article
- Fracture Resistance of Provisional Crowns: A Finite Element Analysis of a Semi-Permanent Resin-A Pilot Study.Dentistry journal · 2025Article
- Assessment of pulpal changes in periodontitis patients using CBCT: a volumetric analysis.Frontiers in dental medicine · 2025Article
- Comparing the technical quality and clinical outcomes of root canal treatment on immature permanent incisors in children: a retrospective evaluation of three bioceramic plug materials.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2024Article
- Dental Luting Cements: An Updated Comprehensive Review.Molecules (Basel, Switzerland) · 2023Review
- Artificial intelligence in dentistry-A review.Frontiers in dental medicine · 2023Review
- Comparison of five single-file systems in the preparation of severely curved root canals: an ex vivo study.BMC oral health · 2022Article
- Pulp blood flow changes in maxillary and mandibular anterior teeth after orthodontic retraction: a prospective study.BMC oral health · 2022Article
- Endodontic treatment of the maxillary first molar with palatal canal variations: A case report and review of literature.World journal of clinical cases · 2022Article
- Assessment of COVID-19 lung involvement on computed tomography by deep-learning-, threshold-, and human reader-based approaches-an international, multi-center comparative study.Quantitative imaging in medicine and surgery · 2022Article
- Synthetic materials in craniofacial regenerative medicine: A comprehensive overview.Frontiers in bioengineering and biotechnology · 2022Review
- Tooth root resorption: A review.Science progressReview
Corrections and comments
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Authors and funding
11 authors at 8 institutions in 6 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The volumetric change that occurs in the pulp space over time represents a critical measure when it comes to determining the secondary outcomes of regenerative endodontic procedures (REPs). However, to date, only a few studies have investigated the accuracy of the available domain-specialized medical imaging tools with regard to three-dimensional (3D) volumetric assessment. This study sought to compare the accuracy of two different artificial intelligence-based medical imaging programs namely OsiriX MD (v 9.0, Pixmeo SARL, Bernex Switzerland, https://www.osirix-viewer.com ) and 3D Slicer ( http://www.slicer.org ), in terms of estimating the volume of the pulp space following a REP. An Invitro assessment was performed to check the reliability and sensitivity of the two medical imaging programs in use. For the subsequent clinical application, pre- and post-procedure cone beam computed tomography scans of 35 immature permanent teeth with necrotic pulp and periradicular pathosis that had been treated with a cell-homing concept-based REP were processed using the two biomedical DICOM software programs (OsiriX MD and 3D Slicer). The volumetric changes in the teeth's pulp spaces were assessed using semi-automated techniques in both programs. The data were statistically analyzed using t-tests and paired t-tests (P = 0.05). The pulp space volumes measured using both programs revealed a statistically significant decrease in the pulp space volume following the REP (P < 0.05), with no significant difference being found between the two programs (P > 0.05). The mean decreases in the pulp space volumes measured using OsiriX MD and 3D Slicer were 25.06% ± 19.45% and 26.10% ± 18.90%, respectively. The open-source software (3D Slicer) was found to be as accurate as the commercially available software with regard to the volumetric assessment of the post-REP pulp space. This study was the first to demonstrate the step-by-step application of 3D Slicer, a user-friendly and easily accessible open-source multiplatform software program for the segmentation and volume estimation of the pulp spaces of teeth treated with REPs.
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