Evidence map›Paper›PMID 34754004›Full record

Trial reportScientific reports2021

Pharmacists' interventions improve health-related quality of life of rural older person on warfarin: a randomized controlled trial.

Slaven Falamić, Marko Lucijanić, Maja Ortner-Hadžiabdić, Srećko Marušić, Vesna Bačić-Vrca

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Article
  6. A rapid review of interventions to improve medicine self-management for older people living at home.Health expectations : an international journal of public participation in health care and health policy · 2023
    Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Slaven FalamićPharmacy Branka Marušić, Trg Ante Starčevića 24, 31450, Donji Miholjac, Croatia.ORCID 0000-0001-7229-3840
Marko LucijanićHematology Department, University Hospital Dubrava, Avenija Gojka Suska 6, 10000, Zagreb, Croatia.
Maja Ortner-HadžiabdićCentre for Applied Pharmacy, Faculty of Pharmacy and Biochemistry, University of Zagreb, Ante Kovačića 1, 10000, Zagreb, Croatia. mortner@pharma.hr.
Srećko MarušićDepartment of Clinical Pharmacology, University Hospital Dubrava, Avenija Gojka Suska 6, 10000, Zagreb, Croatia.
Vesna Bačić-VrcaDepartment of Clinical Pharmacy, University Hospital Dubrava, Avenija Gojka Suska 6, 10000, Zagreb, Croatia.
University Hospital Dubrava · HRUniversity of Zagreb · HR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Warfarin therapy can significantly affect patients' quality of life and cause therapy discontinuation. This study aimed to investigate the effect of the pharmacists' interventions on the health-related quality of life (HRQoL) in older rural patients on warfarin therapy. Eligible older patients from rural area of Croatian province Slavonia were randomized into the intervention and control groups and followed for six months. Repeated education and a follow-up plan were provided to the participants in the intervention group, and if needed, the pharmacist intervened to optimize warfarin therapy. Secondary analysis on HRQoL data are presented here. Main outcome measure was Duke anticoagulation satisfactions scale questionnaire score. In total, 131 participants finished the study (median age 73 years; 51.1% male). Participants in the intervention group scored significantly lower (median being 86.5 and 66.0 in the control and intervention groups, respectively; p < 0,001), indicating higher HRQoL. Adverse drug reactions and pharmacist's intervention were identified as predictive factors for patients' HRQoL (r

Indexed as

Community Pharmacy ServicesQuality of LifeAgedAged, 80 and overAnticoagulantsCroatiaDrug-Related Side Effects and Adverse ReactionsFemaleHumansMalePatient Education as TopicPharmacistsRural PopulationSurveys and QuestionnairesWarfarinAnticoagulantsWarfarin

Identifiers

PMID34754004
PMCPMC8578616
OpenAlexW3212723083

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.