Evidence map›Paper›PMID 34753977›Full record

ArticleScientific reports2021

Multifaceted phytogenic silver nanoparticles by an insectivorous plant Drosera spatulata Labill var. bakoensis and its potential therapeutic applications.

Susmila Aparna Gaddam, Venkata Subbaiah Kotakadi, Gunasekhar Kalavakunta Subramanyam, Josthna Penchalaneni, Varadarajulu Naidu Challagundla, Sai Gopal Dvr, Visweswara Rao Pasupuleti

Abstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Synthesis of Silver Nanoparticles by Leaf Extract ofMolecules (Basel, Switzerland) · 2023
    Article
  7. Review
  8. Article
  9. Nanomaterials (Basel, Switzerland) · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Susmila Aparna Gaddam *Department of Virology, Sri Venkateswara University, Tirupati, Andhra Pradesh, India.
Venkata Subbaiah Kotakadi *DST-PURSE Centre, Sri Venkateswara University, Tirupati, Andhra Pradesh, India. kotakadi72@gmail.com.
Gunasekhar Kalavakunta SubramanyamDepartment of Biotechnology, Dravidian University, Kuppam, Andhra Pradesh, India.
Josthna PenchalaneniDepartment of Biotechnology, Sri Padmavathi Mahila Visvavidyalayam (Women's University), Tirupati, Andhra Pradesh, India.
Varadarajulu Naidu ChallagundlaDepartment of Biotechnology, Dravidian University, Kuppam, Andhra Pradesh, India.
Sai Gopal DvrDepartment of Virology, Sri Venkateswara University, Tirupati, Andhra Pradesh, India.
Visweswara Rao PasupuletiDepartment of Biomedical Sciences and Therapeutics, Universiti Malaysia Sabah, Kota Kinabalu, Sabah, Malaysia. pvrao@ums.edu.my.

Funding

Universitas Abdurrab 065/LPPM/SPKINT/VII/2019Universiti Malaysia Sabah SGA0014-2019
6 · The paper itself

Abstract

The current investigation highlights the green synthesis of silver nanoparticles (AgNPs) by the insectivorous plant Drosera spatulata Labill var. bakoensis, which is the first of its kind. The biosynthesized nanoparticles revealed a UV visible surface plasmon resonance (SPR) band at 427 nm. The natural phytoconstituents which reduce the monovalent silver were identified by FTIR. The particle size of the Ds-AgNPs was detected by the Nanoparticle size analyzer confirms that the average size of nanoparticles was around 23 ± 2 nm. Ds-AgNPs exhibit high stability because of its high negative zeta potential (- 34.1 mV). AFM studies also revealed that the Ds-AgNPs were spherical in shape and average size ranges from 10 to 20 ± 5 nm. TEM analysis also revealed that the average size of Ds-AgNPs was also around 21 ± 4 nm and the shape is roughly spherical and well dispersed. The crystal nature of Ds-AgNPs was detected as a face-centered cube by the XRD analysis. Furthermore, studies on antibacterial and antifungal activities manifested outstanding antimicrobial activities of Ds-AgNPs compared with standard antibiotic Amoxyclav. In addition, demonstration of superior free radical scavenging efficacy coupled with potential in vitro cytotoxic significance on Human colon cancer cell lines (HT-29) suggests that the Ds-AgNPs attain excellent multifunctional therapeutic applications.

Indexed as

Anti-Infective AgentsDroseraFree Radical ScavengersGreen Chemistry TechnologyHT29 CellsHumansMetal NanoparticlesMicrobial Sensitivity TestsParticle SizeSilverSpectrum AnalysisX-Ray DiffractionAnti-Infective AgentsFree Radical ScavengersSilver

Identifiers

PMID34753977
PMCPMC8578548

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.