Evidence map›Paper›PMID 34753900›Full record

Trial reportNutrition & diabetes2021

Egg and saturated fat containing breakfasts have no acute effect on acute glycemic control in healthy adults: a randomized partial crossover trial.

Chathurika S Dhanasekara, John A Dawson, Martin Binks, Allison Childress, Nikhil V Dhurandhar

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Nutrition & diabetes, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 82% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

  • Commented on by
    2022
5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Chathurika S DhanasekaraDepartment of Nutritional Sciences, Texas Tech University, Lubbock, TX, USA.
John A DawsonDepartment of Nutritional Sciences, Texas Tech University, Lubbock, TX, USA.
Martin BinksDepartment of Nutritional Sciences, Texas Tech University, Lubbock, TX, USA.ORCID 0000-0001-8759-4048
Allison ChildressDepartment of Nutritional Sciences, Texas Tech University, Lubbock, TX, USA.ORCID 0000-0002-7831-1760
Nikhil V DhurandharDepartment of Nutritional Sciences, Texas Tech University, Lubbock, TX, USA. Nikhil.Dhurandhar@ttu.edu.ORCID 0000-0002-1356-1064
Texas Tech University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

objectivesHigh egg consumption is associated with poor glycemic control. Considering the widespread consumption of eggs, it is crucial to determine causality in this association. We tested if egg consumption acutely alters glucose disposal in the absence or presence of saturated fat, which is frequently consumed with eggs. SUBJECTS/

methodsIn a randomized partial crossover clinical trial, 48 subjects (consuming ≥ 1 egg/week) received two of four isocaloric, macronutrient-matched breakfasts. The groups were defined based on the main ingredient of the breakfasts offered: eggs (EB); saturated fat (SB); eggs and saturated fat (ES); and control, which included a cereal based breakfast (CB). The breakfasts were offered in two testing sessions spaced seven days apart. Six blood samples (pre breakfast (fasting); 30, 60, 90, 120, and 180 minutes post breakfast) were collected to measure glucose and insulin levels. Area under the curves (AUC) were analyzed controlling for the baseline concentrations using mixed-effects models accounting for within-subject dependencies to compare these across breakfast assignments.

resultsForty-eight patients (46% males, age 25.8 ± 7.7 years, BMI 25.7 ± 4.6 kg/m

conclusionsAcutely, consumption of egg breakfast with or without accompanying saturated fat does not adversely affect glucose disposal in healthy adults. While this is reassuring for continued egg consumption, a long-term evaluation of egg intake with or without saturated fat would be the next step.

Indexed as

BreakfastEggsAdultBlood GlucoseCross-Over StudiesDietary CarbohydratesDietary FatsDietary FiberFastingFatty AcidsFemaleGlycemic ControlGlycemic IndexHumansInsulinMaleBlood GlucoseDietary CarbohydratesDietary FatsDietary FiberFatty AcidsInsulin

Identifiers

PMID34753900
PMCPMC8578538
OpenAlexW3213912449

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.