Evidence map›Paper›PMID 34753818›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2021

The structure of the

Jiangfeng Zhao, Hao Xie, Ahmad Reza Mehdipour, Schara Safarian, Ulrich Ermler, Cornelia Münke, Yvonne Thielmann, Gerhard Hummer, Ingo Ebersberger, Jingkang Wang and 1 more

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.0field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Antimalarial drug discovery: progress and approaches.Nature reviews. Drug discovery · 2023
    Review
  6. CHARMM-GUIJournal of chemical theory and computation · 2023
    Review
  7. Article
  8. Resistance mechanisms of tigecycline inFrontiers in cellular and infection microbiology · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Jiangfeng ZhaoState Key Laboratory for Chemical Engineering, Collaborative Innovation Center of Chemical Science and Chemical Engineering, School of Chemical Engineering and Technology, Tianjin University, 300072 Tianjin, P. R. China.
Hao XieDepartment of Molecular Membrane Biology, Max Planck Institute of Biophysics, 60438 Frankfurt am Main, Germany.
Ahmad Reza MehdipourDepartment of Theoretical Biophysics, Max Planck Institute of Biophysics, 60438 Frankfurt am Main, Germany.
Schara SafarianDepartment of Molecular Membrane Biology, Max Planck Institute of Biophysics, 60438 Frankfurt am Main, Germany.ORCID 0000-0002-0232-1612
Ulrich ErmlerDepartment of Molecular Membrane Biology, Max Planck Institute of Biophysics, 60438 Frankfurt am Main, Germany.
Cornelia MünkeDepartment of Molecular Membrane Biology, Max Planck Institute of Biophysics, 60438 Frankfurt am Main, Germany.
Yvonne ThielmannDepartment of Molecular Membrane Biology, Max Planck Institute of Biophysics, 60438 Frankfurt am Main, Germany.
Gerhard HummerDepartment of Theoretical Biophysics, Max Planck Institute of Biophysics, 60438 Frankfurt am Main, Germany.ORCID 0000-0001-7768-746X
Ingo EbersbergerDepartment for Applied Bioinformatics, Institute for Cell Biology and Neuroscience, Goethe University Frankfurt, 60438 Frankfurt am Main, Germany.
Jingkang WangState Key Laboratory for Chemical Engineering, Collaborative Innovation Center of Chemical Science and Chemical Engineering, School of Chemical Engineering and Technology, Tianjin University, 300072 Tianjin, P. R. China; jkwang@tju.edu.cn hartmut.michel@biophys.mpg.de.
Hartmut MichelDepartment of Molecular Membrane Biology, Max Planck Institute of Biophysics, 60438 Frankfurt am Main, Germany; jkwang@tju.edu.cn hartmut.michel@biophys.mpg.de.ORCID 0000-0003-4351-7846
Max Planck Institute of Biophysics · DETianjin University · CNGoethe University Frankfurt · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Multidrug and toxic compound extrusion (MATE) transporters are widespread in all domains of life. Bacterial MATE transporters confer multidrug resistance by utilizing an electrochemical gradient of H

Indexed as

AquifexBacterial ProteinsBinding SitesDrug Resistance, MultipleMutagenesis, Site-DirectedPhylogenyProkaryotic CellsBacterial Proteinsmembrane protein structuremultidrug resistance transporterphylogenetic analysis

Identifiers

PMID34753818
PMCPMC8609645
OpenAlexW3211615754

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.