Evidence map›Paper›PMID 34753719›Full record

ArticleBMJ case reports2021

Graves' disease associated with cholestatic jaundice and persistent diarrhoea.

Siddhesh Vijay Rane, Ravi Thanage, Sanjay Chandnani, Pravin M Rathi

Open access · greenAbstract readCase Reports
In one paragraph

Article in BMJ case reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.1field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Article
  3. Liver Dysfunction in a Patient with Graves' Disease.Journal of clinical medicine · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Siddhesh Vijay RaneGastroenterology, Topiwala National Medical College, Mumbai, Maharashtra, India sid.6173@gmail.com.
Ravi ThanageGastroenterology, Topiwala National Medical College, Mumbai, Maharashtra, India.
Sanjay ChandnaniGastroenterology, Topiwala National Medical College, Mumbai, Maharashtra, India.
Pravin M RathiGastroenterology, Topiwala National Medical College, Mumbai, Maharashtra, India.
Topiwala National Medical College & BYL Nair Charitable Hospital · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Liver involvement in Graves' disease can be seen as a part of autoimmune process or rarely, due to the direct effects of thyrotoxicosis on liver. Hyperthyroidism can also have gastrointestinal manifestations like frequent bowel movements, diarrhoea, even malabsorption with steatorrhoea. We report a 36-year-old man with hyperthyroidism, presenting with cholestatic jaundice and persistent small bowel diarrhoea. He was diagnosed to have Graves' disease and after ruling out more common causes, the cause of cholestatic jaundice was supposed to be Graves' disease. Considering this possibility, the patient was started on treatment with carbimazole. As patient's thyroid function tests started improving, he showed significant clinical and biochemical improvement from liver point of view as well.

Indexed as

Graves DiseaseJaundice, ObstructiveThyrotoxicosisAdultCarbimazoleDiarrheaHumansMaleCarbimazolehepatitis otherthyrotoxicosis

Identifiers

PMID34753719
PMCPMC8578937
OpenAlexW3214197425

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.