Evidence map›Paper›PMID 34753444›Full record

ArticleBMC medical imaging2021

Revisiting left atrial volumetry by magnetic resonance imaging: the role of atrial shape and 3D angle between left ventricular and left atrial axis.

Jouni K Kuusisto, Pauli A K Pöyhönen, Jani Pirinen, Lauri J Lehmonen, Heli P Räty, Nicolas Martinez-Majander, Jukka Putaala, Juha Sinisalo, Vesa Järvinen

Registry-linked trialOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC medical imaging, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01934725 (Searching for Explanations for Cryptogenic Stroke in the Young), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01934725 active not recruitingnot on this map

Searching for Explanations for Cryptogenic Stroke in the Young: Revealing the Etiology, Triggers, and Outcome (SECRETO)

TypeobservationalSponsorSECRETO Study ConsortiumRan2013 to 2031Enrolled1,200ConditionsBrain Infarction, Ischemic Stroke, Thrombosis, Foramen Ovale, Patent
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Jouni K KuusistoHeart and Lung Center, Helsinki University Hospital and University of Helsinki, Haartmaninkatu 4, PO Box 340, 00029, Helsinki, Finland. jouni.kuusisto@hus.fi.
Pauli A K PöyhönenHeart and Lung Center, Helsinki University Hospital and University of Helsinki, Haartmaninkatu 4, PO Box 340, 00029, Helsinki, Finland.
Jani PirinenHUS Medical Imaging Center, Clinical Physiology and Nuclear Medicine, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.
Lauri J LehmonenHUS Medical Imaging Center, Radiology, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.
Heli P RätyHUS Medical Imaging Center, Clinical Physiology and Nuclear Medicine, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.
Nicolas Martinez-MajanderNeurology, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.
Jukka PutaalaNeurology, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.
Juha SinisaloHeart and Lung Center, Helsinki University Hospital and University of Helsinki, Haartmaninkatu 4, PO Box 340, 00029, Helsinki, Finland.
Vesa JärvinenHUS Medical Imaging Center, Clinical Physiology and Nuclear Medicine, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.
Helsinki University Hospital · FIUniversity of Helsinki · FIHospital District of Helsinki and Uusimaa · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAccurate measurement of left atrial (LA) volumes is needed in cardiac diagnostics and the follow up of heart and valvular diseases. Geometrical assumptions with 2D methods for LA volume estimation contribute to volume misestimation. In this study, we test agreement of 3D and 2D methods of LA volume detection and explore contribution of 3D LA axis orientation and LA shape in introducing error in 2D methods by cardiovascular magnetic resonance imaging.

methods30 patients with prior first-ever ischemic stroke and no known heart disease, and 30 healthy controls were enrolled (age 18-49) in a substudy of a prospective case-control study. All study subjects underwent cardiac magnetic resonance imaging and were pooled for this methodological study. LA volumes were calculated by biplane area-length method from both conventional long axis (LAV

resultsBiases were - 9.9 mL (- 12.5 to - 7.2) for LAV

conclusionsCalculated LA volume accuracy did not improve by using LA long axis-oriented images for volume calculation in comparison to conventional method. We present novel data on LA axis orientation and a novel metric of LA sphericity and conclude that these measures cannot be utilized to assess error in LA volume calculation.

trial registrationMain study Searching for Explanations for Cryptogenic Stroke in the Young: Revealing the Etiology, Triggers, and Outcome (SECRETO; NCT01934725) has been registered previously.

Indexed as

AdolescentAdultCase-Control StudiesFemaleHeart AtriaHeart VentriclesHumansMagnetic Resonance ImagingMaleMiddle AgedOrgan SizeProspective StudiesAxisCardiac magnetic resonance imagingLeft atriumShapeSphericityVolume assessment

Identifiers

PMID34753444
PMCPMC8579555
OpenAlexW3214370122

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.