Evidence map›Paper›PMID 34752767›Full record

ArticleCurrent biology : CB2021

Neuromodulation: A model for dopamine in salience encoding.

Jingyi Chen, Michael Bruchas

Abstract readComment
PubMed Publisher
In one paragraph

Article in Current biology : CB, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Anxiety and depression: A top-down, bottom-up model of circuit function.Annals of the New York Academy of Sciences · 2023
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Jingyi ChenCenter for the Neurobiology of Addiction, Pain, and Emotion, University of Washington, Seattle, WA 98195, USA; Departments of Anesthesiology and Pain Medicine, University of Washington, Seattle, WA 98195, USA.
Michael BruchasCenter for the Neurobiology of Addiction, Pain, and Emotion, University of Washington, Seattle, WA 98195, USA; Departments of Anesthesiology and Pain Medicine, University of Washington, Seattle, WA 98195, USA; Department of Pharmacology, University of Washington, Seattle, WA 98195, USA; Department of Bioengineering, University of Washington, Seattle, WA 98195, USA. Electronic address: mbruchas@uw.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The neurotransmitter dopamine has well-known roles in reward-seeking behaviors: a new study with mice has now revealed that dopamine signaling in the nucleus accumbens core, a region of the basal forebrain, encodes saliency during reinforcement learning.

Indexed as

DopamineNucleus AccumbensAnimalsMiceNeurotransmitter AgentsReinforcement, PsychologyRewardDopamineNeurotransmitter Agents

Identifiers

PMID34752767

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.