Evidence map›Paper›PMID 34752744›Full record

ArticleDevelopmental cell2021

Giving translation a hand.

Ethan C Strayer, Valerie A Tornini, Antonio J Giraldez

Open access · bronzeAbstract readComment
In one paragraph

Article in Developmental cell, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 89% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Ethan C StrayerDepartment of Genetics, Yale University School of Medicine, New Haven, CT 06510, USA.
Valerie A TorniniDepartment of Genetics, Yale University School of Medicine, New Haven, CT 06510, USA.
Antonio J GiraldezDepartment of Genetics, Yale University School of Medicine, New Haven, CT 06510, USA; Yale Stem Cell Center, Yale University School of Medicine, New Haven, CT 06510, USA; Yale Cancer Center, Yale University School of Medicine, New Haven, CT 06510, USA. Electronic address: antonio.giraldez@yale.edu.
Yale University · USYale Cancer Center · US

Funding

Molecular mechanisms of the maternal to zygotic transitionR35GM122580 · NIGMS · YALE UNIVERSITY · PI Antonio J Giraldez · 2017 to 2026
$8.1M
Deciphering the regulatory code that specifies different cell fates in development using single cell genomicsR01HD100035 · NICHD · YALE UNIVERSITY · PI GIRALDEZ, ANTONIO J, KRISHNASWAMY, SMITA · 2020 to 2024
$2.8M
Functional analysis of the zebrafish genome through RNA-seq and ribosome profileR01HD074078 · NICHD · YALE UNIVERSITY · PI GIRALDEZ, ANTONIO J · 2012 to 2016
$2.3M
NICHD NIH HHS R01 HD074078NICHD NIH HHS R01 HD100035NIGMS NIH HHS R35 GM122580
6 · The paper itself

Abstract

A cell's identity is commonly regarded as its transcriptomic profile. In this issue of Developmental Cell, Fujii et al. (2021) show that a global translation factor subunit acts differentially on transcripts to modulate morphogen signaling levels, revealing a global mechanism of transcript-specific translational control in development.

Identifiers

PMID34752744
PMCPMC10519192
OpenAlexW3211725318

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.