ReviewAnnual review of physiology2022
The Cellular and Molecular Basis of Sour Taste.
Review in Annual review of physiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 31 citations in OpenAlex.
- Effects of Oral Health and Functional Characteristics on Taste Sensitivity in Older Adults: Comparative Analysis Using Solution and Taste Strip Tests.Journal of oral rehabilitation · 2026Article
- A brain stem circuit integrating reflexive and anticipatory salivation.Cell reports · 2026Article
- The intra-oral variation of salivary ions.Clinical oral investigations · 2025Article
- The enigma of type III taste bud cells.The Journal of physiology · 2025Article
- Dual functions of SNAP25 in mouse taste buds.The Journal of physiology · 2025Article
- Mouthfeel of Food and Beverages: A Comprehensive Review of Physiology, Biochemistry, and Key Sensory Compounds.Comprehensive reviews in food science and food safety · 2025Review
- Roles of sensory receptors in non-sensory organs: the kidney and beyond.Nature reviews. Nephrology · 2025Review
- Perception of Sour Taste in Subjects with Olfactory Deficits: Role of Myrtle Aromatization.Nutrients · 2024Article
- FlavorMiner: a machine learning platform for extracting molecular flavor profiles from structural data.Journal of cheminformatics · 2024Article
- The proton channel OTOP1 is a sensor for the taste of ammonium chloride.Nature communications · 2023Article
- Widely targeted metabolomics analysis of different Wuyi Shuixian teas and association with taste attributes.Heliyon · 2023Article
- Interkingdom Detection of Bacterial Quorum-Sensing Molecules by Mammalian Taste Receptors.Microorganisms · 2023Review
- Physiology of the tongue with emphasis on taste transduction.Physiological reviews · 2023Review
- Nematode homologs of the sour taste receptor Otopetrin1 are evolutionarily conserved acid-sensitive proton channels.Frontiers in cell and developmental biology · 2023Article
- Effect of Sinus Perforation with Flaplessly Placed Mini Dental Implants for Oral Rehabilitation: A 5-Year Clinical and Radiological Follow-Up.Journal of clinical medicine · 2022Article
- Not Only COVID-19: Involvement of Multiple Chemosensory Systems in Human Diseases.Frontiers in neural circuits · 2022Review
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Sour taste, the taste of acids, is one of the most enigmatic of the five basic taste qualities; its function is unclear and its receptor was until recently unknown. Sour tastes are transduced in taste buds on the tongue and palate epithelium by a subset of taste receptor cells, known as type III cells. Type III cells express a number of unique markers, which allow for their identification and manipulation. These cells respond to acid stimuli with action potentials and release neurotransmitters onto afferent nerve fibers, with cell bodies in geniculate and petrosal ganglia. Here, we review classical studies of sour taste leading up to the identification of the sour receptor as the proton channel OTOP1.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.