ArticlePloS one2021
Usefulness of Hamilton rating scale for depression subset scales and full versions for electroconvulsive therapy.
Article in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01907217 (A Randomised Controlled Trial of Standard Bilateral Electroconvulsive Therapy Versus High-dose Unilateral Electroconvulsive Therapy for Severe Depression), which is not on this map. Cited by 12 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Randomised Controlled Trial of Standard Bilateral Electroconvulsive Therapy Versus High-dose Unilateral Electroconvulsive Therapy for Severe Depression
Who cites it
12 citing papers in PubMed.
- Efficacy of empagliflozin as adjunctive therapy to citalopram in major depressive disorder: a randomized double-blind, placebo-controlled clinical trial.BMC psychiatry · 2024Trial
- The effects of solution-focused group therapy on peer friendship quality in adolescents with anxiety disorders.Frontiers in psychology · 2026Article
- Sequential bilateral rTMS combined with fluoxetine for anhedonic depression in adolescents: clinical efficacy and peripheral inflammatory profiles.Frontiers in psychiatry · 2026Article
- Exploring New Frontiers in Pharmacological Treatment of Depression: A Review on Recent Advances.Current medicinal chemistry · 2026Review
- Direct and indirect associations of hypochondriasis with suicidality in psychiatric outpatients: mediating roles of anxiety and depression.Frontiers in psychiatry · 2026Article
- [Influence of Exercise Prescription on the Recovery of Cognitive Function In College Students With Mild-to-Moderate Depression].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2025Article
- The Significance of Psychological Support in Managing Depression in Parkinson's Disease: Combining Venlafaxine with Pramipexole and Psychological Care.Actas espanolas de psiquiatria · 2025Article
- Exploring the Characteristics of Gut Microbiota Associated with Depression via the Depression Assessment Scales.Journal of microbiology and biotechnology · 2024Article
- Development of a differential treatment selection model for depression on consolidated and transformed clinical trial datasets.Translational psychiatry · 2024Article
- EEG microstate as a biomarker of post-stroke depression with acupuncture treatment.Frontiers in neurology · 2024Article
- Consanguinity and Nonsuicidal Self-Injury in Depressed Patients: New Risk Factors and Risk Prediction Models.Alpha psychiatry · 2024Article
- Effect of internet multiple linkage mode-based extended care combined with in-hospital comfort care on colorectal cancer patients undergoing colostomy.World journal of gastrointestinal surgery · 2023Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesWe investigated the predictive value of subset scales and full versions of the Hamilton Rating Scale for Depression (HAMD) for therapeutic outcomes in ECT.
methodsThis secondary analysis of patients with major depression (N = 136; 63% female; age = 56.7 [SD = 14.8]) from the EFFECT-Dep trial (NCT01907217) examined the predictive value of Evans-6, Toronto-7, Gibbons-8 and Maier-Philip 6 HAMD subset scales and three 'full' versions (HAMD-17, HAMD-21 and HAMD-24) on therapeutic outcomes. We also examined early improvement on subset scales and full versions as predictors of response and remission and explored predictive abilities of individual HAMD-24 items.
resultsThe subset scales and full scales lacked sufficient predictive ability for response and remission. Receiver operating characteristic curves identified a lack of discriminative capacity of HAMD subset scales and full versions at baseline to predict response and remission. Only the Maier-Philip-6 was significantly associated with percentage reduction in HAMD-24 scores from baseline to end of ECT course. Early improvement on most of the subset scales and full versions was a sensitive and specific predictor of response and remission. Four of the HAMD-24 items were significantly associated with response and one with remission.
conclusionsLimited utility of the HAMD subset scales and full versions in this context highlight a need for more tailored depression rating scales for ECT.
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